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Abstract drawing of microbes.
Exploring Microbial Dark Matter
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 
Exploring Microbial Dark Matter
Exploring Microbial Dark Matter

An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 

An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds. 

metabolism

The illustration shows adipocytes, cells of the adipose tissue, and Trypanosoma brucei parasites that occupy the extracellular spaces between the cells.
Lose the Fat and Curb Parasitic Infection
Mariella Bodemeier Loayza Careaga, PhD | Mar 1, 2024 | 2 min read
Trypanosoma brucei infection induces fat breakdown, but this strategy benefits the host. 
A hummingbird hovers next to a red and yellow feeder.
Why Don’t Hummingbirds Get Diabetes?
Hannah Thomasy, PhD | Feb 1, 2024 | 2 min read
Astronomically high blood sugar is no problem for these tiny speed demons.
An Introduction to Metabolomics
An Introduction to Metabolomics
Rebecca Roberts, PhD | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
Close-up image of fat cells
A Snapshot of How Obesity Transforms Fat
Aparna Nathan, PhD | Oct 5, 2023 | 3 min read
Spatial methods reveal immune cell formations in fat during early obesity.
Dendritic Cell activate T cells, trigger immune responses, they are responsible of cells protection of the body.
Circadian Signaling Affects T Cell Responses to Vaccination
Nathan Ni, PhD | Aug 9, 2023 | 3 min read
Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.
Learn how recombinant proteins move the diagnostic industry forward
Emergent Recombinant Proteins in Clinical Diagnostics
Scripps Laboratories | 1 min read
A new era of reliable recombinant proteins makes it possible for researchers to replace tissue-derived biomarkers in a variety of diagnostic assays.
Mouse running on wheel
An Exercise-induced Liver Enzyme Boosts Metabolism
Natalia Mesa, PhD | Jul 7, 2023 | 3 min read
Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice. 
Image of yeast cells
Yeast Cells Reconfigure Their Metabolomes to Live Longer
Danielle Gerhard, PhD | Jul 5, 2023 | 2 min read
Yeast cells share metabolites through extracellular space to extend the lifespan of the entire community.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
Man in blue shirt holding a paper representation of the intestines
Gut Bacteria Contribute to Anorexia
Kamal Nahas, PhD | May 1, 2023 | 3 min read
Microbiomes transplanted from women with anorexia nervosa into mice enhanced symptoms of the eating disorder, such as rapid weight loss and reduced appetite.
Histology of brain
Rare Autism-Linked Mutation Starves Growing Neurons of Essential Nutrients
Lauren Schenkman, Spectrum | Apr 18, 2023 | 4 min read
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
The Scientist and PerkinElmer | 1 min read
Robin Ketteler and Hélène Plun-Favreau discuss the importance of autophagy and mitophagy regulation in neurodegenerative diseases.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
Staphylococcus aureus bacteria on the skin
The Scientist Speaks - Virulence Meets Metabolism: The Unique Evolution of Staphylococcus aureus
Niki Spahich, PhD | 1 min read
Anthony Richardson discusses what makes Staph especially dangerous for people with diabetes.
Turkey, mashed potatoes, stuffing, pumpkin pie and sides on a table
The Smell of Food Affects Metabolism in Fasting Mice
Shafaq Zia | Nov 18, 2022 | 3 min read
The odor prompted the animals’ fat cells to release lipids into circulation.
Illustration of green fluorescent bacterial cells.
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
Alejandra Manjarrez, PhD | Nov 1, 2022 | 3 min read
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
Examine Altered Glycobiology in Cancer
Examining Altered Glycobiology in Cancer
The Scientist and Vector Laboratories | 1 min read
Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets?
Man with blue shirt and tie smiling at camera.
Pharmacologist and Olympian David Bailey Dies at 77
Lisa Winter | Oct 7, 2022 | 3 min read
He was best known for his discovery that grapefruit juice makes some medications less effective or potentially dangerous.
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