News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
Big Data in 3 Dimensions
Jim Daley | May 1, 2018
Viewing oncogenic mutations in 3-D showed that they cluster together on folded proteins.
Caloric Restriction Slows Signs of Aging in Humans
Diana Kwon | Mar 26, 2018
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
How Gaining and Losing Weight Affects the Body
Abby Olena | Jan 17, 2018
Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.
High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
Olfaction Determines Weight in Mice
Diana Kwon | Jul 5, 2017
Animals lacking a sense of smell stayed thinner than their smelling counterparts, despite eating the same amount.
Mammals May Have a 12-Hour Clock
Ashley Yeager | Jun 6, 2017
Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.
Running on Empty
Bob Grant | Jun 1, 2017
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.