One variant limited the brain’s ability to use glucose.

Timekeepers in muscle help mediate metabolism, and may influence neurological processes such as sleep.

Just 20 years ago, scientists didn’t even realize muscles had their own circadian clocks. Now they are beginning to appreciate their importance in health. 

Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.

Viewing oncogenic mutations in 3-D showed that they cluster together on folded proteins.

Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.