metabolic disease

A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.

Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.

Lactation boosts the quantity and quality of insulin-producing beta cells in the pancreas, likely reducing a woman’s risk of developing type 2 diabetes.

Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.

Limiting food intake leads to the conversion of white fat cells into more metabolically active brown fat cells through an immune response, a mouse study shows.

The results of studies on humans and zebrafish suggest how hyperglycemia can cause cognitive deficits.

Researchers unveil the most comprehensive atlas of genes underlying human metabolic pathways, paving the way for improved understanding and treatment of metabolic diseases.

Why eating at the wrong times is tied to such profound and negative effects on our bodies

Circadian time zones and metabolism

Many of the body's tissues can tell time, and these peripheral clocks can be influenced by environmental cues, such as the timing of food consumption.

Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.

Meet some of the people featured in the December 2012 issue of The Scientist.

Research suggesting that antibiotics given to young children may increase obesity spurs scientific debate

Researchers in the U.K. are looking to breed marijuana to make medicines for metabolic disorders, epilepsy, and other diseases.

Malnutrition continues to be a problem for people living without stable homes, but it is beginning to be accompanied by obesity.

Exercise causes short-term changes in DNA methylation and gene expression in muscle tissue that may have implications for type 2 diabetes.

Untargeted metabolic profiling implicates a new suite of metabolites that may be involved in nerve damage-induced pain.