Leon Rosenberg in a grey sports coat
Physician and Geneticist Leon Rosenberg Dies at 89
He advanced the field of medical genetics, spoke out about reducing the stigma associated with mental illness, and captured attention for asserting that scientific evidence failed to demonstrate that life begins at conception.
Physician and Geneticist Leon Rosenberg Dies at 89
Physician and Geneticist Leon Rosenberg Dies at 89

He advanced the field of medical genetics, spoke out about reducing the stigma associated with mental illness, and captured attention for asserting that scientific evidence failed to demonstrate that life begins at conception.

He advanced the field of medical genetics, spoke out about reducing the stigma associated with mental illness, and captured attention for asserting that scientific evidence failed to demonstrate that life begins at conception.

metabolic disease
Micrograph of a beta cell, where insulin granules are shown as blue small balls, mitochondria are colored green, and a fraction of the cell nucleus appears in purple.
Diabetes Linked to Malnutrition Is Metabolically Unique: Study
Alejandra Manjarrez | Jun 16, 2022
Results from a small sample of Indian males suggest that lean individuals with a history of malnutrition suffer from a distinct type of diabetes characterized by a defect in insulin secretion.
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease
The Scientist Speaks - Lipids Predict a Slippery Path Towards Parkinson’s Disease
Nele Haelterman, PhD
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease.
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena | Aug 6, 2021
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
A black mouse runs on a yellow and green spinning wheel against a blue background
Exercising During Pregnancy Protects Mouse Offspring
Jack J. Lee | Aug 1, 2021
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.
image-2021-08-16-08-24-55-620
Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?
Roni Dengler, PhD
Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria.
How Breastfeeding Protects Mothers
Rachael Moeller Gorman | Jul 13, 2020
Lactation boosts the quantity and quality of insulin-producing beta cells in the pancreas, likely reducing a woman’s risk of developing type 2 diabetes.
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
Caloric Restriction Turns White Fat Brown
Alison F. Takemura | Aug 25, 2016
Limiting food intake leads to the conversion of white fat cells into more metabolically active brown fat cells through an immune response, a mouse study shows.
How Type 2 Diabetes Affects the Brain
Mallory Locklear | Jul 20, 2016
The results of studies on humans and zebrafish suggest how hyperglycemia can cause cognitive deficits.
Metabolism Mapped
Bob Grant | May 12, 2014
Researchers unveil the most comprehensive atlas of genes underlying human metabolic pathways, paving the way for improved understanding and treatment of metabolic diseases.
Out of Sync
Kerry Grens | Sep 1, 2013
Why eating at the wrong times is tied to such profound and negative effects on our bodies
You Are When You Eat
Mary Beth Aberlin | Sep 1, 2013
Circadian time zones and metabolism
Mind the Clock
Kerry Grens | Aug 31, 2013
Many of the body's tissues can tell time, and these peripheral clocks can be influenced by environmental cues, such as the timing of food consumption.
Fat's Immune Sentinels
Justin Odegaard and Ajay Chawla | Dec 1, 2012
Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.
Contributors
Beth Marie Mole | Dec 1, 2012
Meet some of the people featured in the December 2012 issue of The Scientist.
Could Drugs be Plumping up Kids?
Edyta Zielinska | Aug 23, 2012
Research suggesting that antibiotics given to young children may increase obesity spurs scientific debate
Cannabis Catch-All?
Jef Akst | Jun 20, 2012
Researchers in the U.K. are looking to breed marijuana to make medicines for metabolic disorders, epilepsy, and other diseases.
Overweight Homeless
Edyta Zielinska | Jun 6, 2012
Malnutrition continues to be a problem for people living without stable homes, but it is beginning to be accompanied by obesity.