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Turkey, mashed potatoes, stuffing, pumpkin pie and sides on a table
The Smell of Food Affects Metabolism in Fasting Mice
The odor prompted the animals’ fat cells to release lipids into circulation.
The Smell of Food Affects Metabolism in Fasting Mice
The Smell of Food Affects Metabolism in Fasting Mice

The odor prompted the animals’ fat cells to release lipids into circulation.

The odor prompted the animals’ fat cells to release lipids into circulation.

metabolic disease
Leon Rosenberg in a grey sports coat
Physician and Geneticist Leon Rosenberg Dies at 89
Andy Carstens | Aug 3, 2022 | 3 min read
He advanced the field of medical genetics, spoke out about reducing the stigma associated with mental illness, and captured attention for asserting that scientific evidence failed to demonstrate that life begins at conception.
Micrograph of a beta cell, where insulin granules are shown as blue small balls, mitochondria are colored green, and a fraction of the cell nucleus appears in purple.
Diabetes Linked to Malnutrition Is Metabolically Unique: Study
Alejandra Manjarrez, PhD | Jun 16, 2022 | 5 min read
Results from a small sample of Indian males suggest that lean individuals with a history of malnutrition suffer from a distinct type of diabetes characterized by a defect in insulin secretion.
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease
The Scientist Speaks - Lipids Predict a Slippery Path Towards Parkinson’s Disease
Nele Haelterman, PhD | 1 min read
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease.
Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021 | 3 min read
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena, PhD | Aug 6, 2021 | 4 min read
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
image-2021-08-16-08-24-55-620
Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?
Roni Dengler, PhD | 2 min read
Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria.
A black mouse runs on a yellow and green spinning wheel against a blue background
Exercising During Pregnancy Protects Mouse Offspring
Jack J. Lee | Aug 1, 2021 | 2 min read
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.
How Breastfeeding Protects Mothers
Rachael Moeller Gorman | Jul 13, 2020 | 3 min read
Lactation boosts the quantity and quality of insulin-producing beta cells in the pancreas, likely reducing a woman’s risk of developing type 2 diabetes.
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018 | 2 min read
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
Caloric Restriction Turns White Fat Brown
Alison F. Takemura | Aug 25, 2016 | 4 min read
Limiting food intake leads to the conversion of white fat cells into more metabolically active brown fat cells through an immune response, a mouse study shows.
How Type 2 Diabetes Affects the Brain
Mallory Locklear | Jul 20, 2016 | 3 min read
The results of studies on humans and zebrafish suggest how hyperglycemia can cause cognitive deficits.
Metabolism Mapped
Bob Grant | May 12, 2014 | 1 min read
Researchers unveil the most comprehensive atlas of genes underlying human metabolic pathways, paving the way for improved understanding and treatment of metabolic diseases.
Out of Sync
Kerry Grens | Sep 1, 2013 | 10+ min read
Why eating at the wrong times is tied to such profound and negative effects on our bodies
You Are When You Eat
Mary Beth Aberlin | Sep 1, 2013 | 3 min read
Circadian time zones and metabolism
Mind the Clock
Kerry Grens | Aug 31, 2013 | 1 min read
Many of the body's tissues can tell time, and these peripheral clocks can be influenced by environmental cues, such as the timing of food consumption.
Fat's Immune Sentinels
Justin Odegaard and Ajay Chawla | Dec 1, 2012 | 10 min read
Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.
Contributors
Beth Marie Mole | Dec 1, 2012 | 3 min read
Meet some of the people featured in the December 2012 issue of The Scientist.
Could Drugs be Plumping up Kids?
Edyta Zielinska | Aug 23, 2012 | 2 min read
Research suggesting that antibiotics given to young children may increase obesity spurs scientific debate
Cannabis Catch-All?
Jef Akst | Jun 20, 2012 | 1 min read
Researchers in the U.K. are looking to breed marijuana to make medicines for metabolic disorders, epilepsy, and other diseases.
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