The Smell of Food Affects Metabolism in Fasting Mice

The odor prompted the animals’ fat cells to release lipids into circulation.

Written byShafaq Zia
| 3 min read
Turkey, mashed potatoes, stuffing, pumpkin pie and sides on a table
Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

The sense of smell is particularly important to many animals, such as mice, in their search for food. But food odor does more than give these animals information about their environment: It also affects their body’s use of fats, a study published Monday (November 14) in Nature Metabolism suggests.

This work, led by Toshiyasu Sasaoka at the University of Toyama in Japan, offers new insights into the neural pathways that link smell perception to adjustments in how efficiently the body turns food into energy, known as metabolic adaptation, according to Minhong Ma, a neuroscientist at University of Pennsylvania who wasn’t involved in the study. The authors of the study did not respond to requests for an interview.

Prior research has shown a close relationship between olfactory neurons, which detect smells and convey this sensory information to our brains, and metabolism. For example, a 2017 study revealed that mice that had ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Shafaq Zia

    Shafaq Zia is a freelance science journalist and a graduate student in the Science Writing Program at the Massachusetts Institute of Technology. Previously, she was a reporting intern at STAT, where she covered the COVID-19 pandemic and the latest research in health technology. Read more of her work here.

    View Full Profile
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH