blood brain barrier

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.

Stressed cells can form hollow actin bridges to neighbors to get help, but the virus may hijack these tiny tunnels for its own purposes, a study suggests.

How scientists aim to induce an immune response against addictive drugs

Researchers are turning to the immune system for help in treating addiction and preventing overdose.

Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.

RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.

Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.

Authors of a new review urge researchers to consider how the chromosomal sex of a cell affects experiments in research on neurodegeneration.

Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.

Several routes exist for immune cells to communicate with neurons in the central nervous system, though T cells rarely come in direct contact with neural tissue.

When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.

A Phase 1 clinical trial shows the noninvasive technique is safe and could aid in the delivery treatments to the brain.

Researchers use a combination of ultrasound waves, genetic engineering, and synthetic drugs to switch specific neurons on and off in mice.

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

Scientists designed autonomous nanovesicles capable of following glucose concentration gradients, even through the blood brain barrier in rats.