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Brush Up: Hematopoietic Stem Cells and Their Role in Development and Disease Therapy
Brush Up: Hematopoietic Stem Cells and Their Role in Development and Disease Therapy
Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis
Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis
bone marrow
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
Infographic: Steps in Cancer Metastasis
Shawna Williams | Apr 1, 2021 | 2 min read
It’s now thought that in many cases, cancer cells disseminate from the primary tumor site early on and lie dormant for long periods rather than only venturing out from primary tumors at an advanced stage.
The MSC: Regeneration Orchestrator
The Scientist Staff | Nov 16, 2020 | 7 min read
Scientists uncover the promise of mesenchymal stem cells (MSCs), also known as medicinal signaling cells, to modulate the immune system and regenerate tissue.
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020 | 1 min read
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
Multiomic Single-Cell Analysis Identifies a Unique Stem and Progenitor Population
The Scientist’s Creative Services Team | Jul 14, 2020 | 2 min read
Margaret Nakamoto will introduce the BD Rhapsody™ Single-Cell Analysis System, and Ravi Majeti will discuss how he and his team used concurrent RNA and BD® AbSeq Antibody-oligo multiplexed surface marker analysis to improve HSPC clustering and characterize specific phenotypic states along unique hematopoietic differentiation trajectories.
Image of the Day: Powerful Protein
Chia-Yi Hou | Apr 25, 2019 | 1 min read
An experiment tests whether a protein treatment can help hematopoietic stem cells recover after mice are exposed to radiation.
Human Skeletal Stem Cell Found
Abby Olena, PhD | Sep 20, 2018 | 3 min read
Researchers recovered the cells that give rise to bone and cartilage from fetal and adult bone marrow and also derived them from induced pluripotent stem cells.
Vitamin C Blocks Leukemia Progression in Mice
Aggie Mika | Aug 17, 2017 | 3 min read
High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.
Image of the Day: Dial M for Murder
The Scientist Staff | Aug 16, 2017 | 1 min read
M proteins from Streptococcus bacteria selectively kill mouse macrophages and human macrophage-like cells by prompting cell death.