News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
Caloric Restriction Slows Signs of Aging in Humans
Diana Kwon | Mar 26, 2018
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
Caloric Restriction Turns White Fat Brown
Alison F. Takemura | Aug 25, 2016
Limiting food intake leads to the conversion of white fat cells into more metabolically active brown fat cells through an immune response, a mouse study shows.
Arrested Development Makes for Long-Lived Worms
Jyoti Madhusoodanan | Jun 23, 2014
Starvation suspends cellular activity in
larvae and extends their lifespan.
Eat Less and Live Longer?
Debamita Chatterjee | Aug 13, 2013
Mice on a low-calorie diet harbor a distinct population of gut microorganisms that helps prolong life.
Sensing Calories Without Taste
Francie Diep | Apr 22, 2013
Rodents and fruit flies appear to be able to sense nutrients even when they can’t taste the food they’re eating. Now, researchers are trying to figure out how.
Kerry Grens | Jan 31, 2013
The eating schedule—and not the amount of calories—can make the difference between an obese, diabetic, sick mouse and one with a healthy metabolism.
Dieting Monkeys Don't Live Longer
Sabrina Richards | Aug 29, 2012
The latest news from a long-term study of calorie restriction in rhesus macaques shows better health, but no boost in lifespan, in monkeys who eat less.
Fasting Heightens Chemotherapy Benefits
Hannah Waters | Feb 8, 2012
Starvation paired with cancer drugs slowed or stopped unchecked cell growth in yeast and mouse models of cancer, outpacing or matching the isolated effects of chemo.
Anti-aging Pathway Questioned
Tia Ghose | Sep 21, 2011
A new study raises further doubts about the ability of proteins called sirtuins to slow aging, but the controversy remains unsettled.