Cas9
Jeremy Day Probes Reward Signaling in the Brain
Jeremy Day Probes Reward Signaling in the Brain
Catherine Offord | Jan 1, 2017
The University of Alabama, Birmingham, researcher seeks the neural roots of animal behavior
More Anti-CRISPR Proteins to Block Cas9
More Anti-CRISPR Proteins to Block Cas9
Kerry Grens | Dec 29, 2016
The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.
New CRISPR-Cas Enzymes Discovered
New CRISPR-Cas Enzymes Discovered
Kerry Grens | Dec 22, 2016
A metagenomics analysis finds Cas9 in archaea for the first time, along with two previously unknown Cas nucleases from bacteria.
Keeping CRISPR in Check
Keeping CRISPR in Check
Anna Azvolinsky | Dec 14, 2016
In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells. 
CRISPR Oral Arguments Recap, Cont’d
CRISPR Oral Arguments Recap, Cont’d
Jef Akst | Dec 8, 2016
This week’s CRISPR patent hearing took a deep dive into the science of moving the gene-editing technology from prokaryotes to eukaryotic systems.
Top 10 Innovations 2016Top 10 Innovations 2016Top 10 Innovations 2016
Top 10 Innovations 2016
The Scientist Staff | Dec 1, 2016
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
Targeting the Noncoding Genome with CRISPR
Targeting the Noncoding Genome with CRISPR
Anna Azvolinsky | Sep 29, 2016
Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes. 
Toggling CRISPR Activity with a Chemical Switch
Toggling CRISPR Activity with a Chemical Switch
Kerry Grens | Sep 12, 2016
Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.
RNA-Targeting CRISPR
RNA-Targeting CRISPR
Anna Azvolinsky | Jun 2, 2016
Scientists identify a novel CRISPR system that zeroes in on single-stranded RNA.  
Gene Editing Without Foreign DNA
Gene Editing Without Foreign DNA
Ruth Williams | Feb 1, 2016
Scientists perform plant-genome modifications on crops without using plasmids.