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Smallest Cas9 Ortholog Reported
Tracy Vence | Feb 23, 2017
Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.
Jeremy Day Probes Reward Signaling in the Brain
Catherine Offord | Jan 1, 2017
The University of Alabama, Birmingham, researcher seeks the neural roots of animal behavior
More Anti-CRISPR Proteins to Block Cas9
Kerry Grens | Dec 29, 2016
The latest CRISPR deactivators to be discovered turn off the
Cas9 widely used in genome editing.
New CRISPR-Cas Enzymes Discovered
Kerry Grens | Dec 22, 2016
A metagenomics analysis finds Cas9 in archaea for the first time, along with two previously unknown Cas nucleases from bacteria.
Keeping CRISPR in Check
Anna Azvolinsky | Dec 14, 2016
In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells.
CRISPR Oral Arguments Recap, Cont’d
Jef Akst | Dec 8, 2016
This week’s CRISPR patent hearing took a deep dive into the science of moving the gene-editing technology from prokaryotes to eukaryotic systems.
Top 10 Innovations 2016
Staff | Dec 1, 2016
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
Targeting the Noncoding Genome with CRISPR
Anna Azvolinsky | Sep 29, 2016
Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes.
Toggling CRISPR Activity with a Chemical Switch
Kerry Grens | Sep 12, 2016
Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.
Anna Azvolinsky | Jun 2, 2016
Scientists identify a novel CRISPR system that zeroes in on single-stranded RNA.