Cas9

CASGEVY^® is the first cell therapy based on the CRISPR/Cas9 technology, discoverers of which were awarded the Nobel Prize in Chemistry in 2020.

In this webinar, Jacob Lamberth will discuss the critical variables and strategies for revolutionizing gene editing experiments.

In this webinar, Jacob Lamberth will discuss the critical variables and strategies for revolutionizing gene editing experiments.

New research reveals how cells prevent telomerase from meddling with double-stranded breaks.

Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.

Scientists combine microplate readers and cell-based assays for high throughput and reduced variability across a variety of applications.

Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.

Researchers optimize their transfection protocols with the ideal transfection reagent that has multiple applications, low cytotoxicity, and high transfection efficiency.

Explore the latest in commercial cell therapy manufacturing processes.

A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.

The approach, called GRAND, uses a second guide RNA to write complementary strands of DNA in targeted genomic locations, resulting in efficient insertions that can be hundreds of base pairs long.

A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.

Examining the major differences between Cas9 and Cas12

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

Experience the past, present, and future of CRISPR technology.

The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.

A CRISPR-based, paper-strip test developed by Indian researchers performs as well as real-time PCR in identifying the presence of SARS-CoV-2 and returns results within an hour.