Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice
The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.
Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

circadian clocks
How Early-Morning Light Exposure Makes Mice Less Depressed
How Early-Morning Light Exposure Makes Mice Less Depressed
Bianca Nogrady | Jul 22, 2021
A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.
Malaria Parasites’ Biological Clocks Coordinate Cell Destruction
Malaria Parasites’ Biological Clocks Coordinate Cell Destruction
Abby Olena | May 14, 2020
Two studies show that Plasmodium—the genus of protozoans that cause malaria—have an internal sense of time that synchronizes with their host’s circadian rhythms and allows the parasites to collectively attack blood cells.
Light Enables Long-Term Memory Maintenance in Fruit Flies
Light Enables Long-Term Memory Maintenance in Fruit Flies
Diana Kwon | May 1, 2020
Under constant darkness, Drosophila’s ability to form lasting memories is impaired.
Into the Light: A Profile of Joanne Chory
Into the Light: A Profile of Joanne Chory
Emily Makowski | Mar 1, 2020
The plant geneticist has revolutionized researchers’ understanding of how light affects plant growth and development, and is engineering plants to combat climate change.
Circadian Clock Genes Help a Crop Pest Adapt to Climate Change
Circadian Clock Genes Help a Crop Pest Adapt to Climate Change
Emily Makowski | Jan 13, 2020
As global temperatures rise and winters shorten, caterpillars of the corn borer moth are emerging earlier in parts of the US thanks to changes in two genes, researchers find.
Microbes Shape Circadian Rhythms in the Mouse Gut
Microbes Shape Circadian Rhythms in the Mouse Gut
Kerry Grens | Sep 27, 2019
The diurnal cycles of the microbiome alter the activity of a protein produced by the host, and in turn guide histone acetylation, gene expression, and metabolic activity.
People at Rest Burn More Calories in the Afternoon
People at Rest Burn More Calories in the Afternoon
Shawna Williams | Nov 8, 2018
Circadian rhythms heavily influence how our bodies use energy, a small study suggests.
Infographic: The Role of Circadian Clocks in Muscle
Infographic: The Role of Circadian Clocks in Muscle
Diana Kwon | Sep 1, 2018
Timekeepers in muscle help mediate metabolism, and may influence neurological processes such as sleep.
Muscle Clocks Play a Role in Regulating Metabolism
Muscle Clocks Play a Role in Regulating Metabolism
Diana Kwon | Sep 1, 2018
Just 20 years ago, scientists didn’t even realize muscles had their own circadian clocks. Now they are beginning to appreciate their importance in health. 
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena | Aug 30, 2018
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.
Fly’s Blood-Brain Barrier Has Circadian Rhythms
Fly’s Blood-Brain Barrier Has Circadian Rhythms
Abby Olena | Mar 8, 2018
In Drosophila, the tissue is more permeable to drugs at night, offering a possible explanation for why some medicines work better at certain times of day.
Why Afternoon Open Heart Surgery Is Better for Patient Outcomes
Why Afternoon Open Heart Surgery Is Better for Patient Outcomes
Catherine Offord | Oct 27, 2017
Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.
Circadian Gene Linked to Severe Epilepsy in Children
Circadian Gene Linked to Severe Epilepsy in Children
Diana Kwon | Oct 11, 2017
Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.
Q&A with Michael Young, Nobel Laureate
Q&A with Michael Young, Nobel Laureate
Ashley P. Taylor | Oct 2, 2017
Young talks with The Scientist about studying circadian rhythms in fruit flies, the applications of his work beyond Drosophila, and winning the prize. 
Q&A with Nobel Laureate Michael Rosbash
Q&A with Nobel Laureate Michael Rosbash
Ashley Yeager | Oct 2, 2017
A basic curiosity about how life works led the Brandeis University molecular biologist to discover how our bodies keep time. 
Giants of Circadian Biology Win Nobel Prize
Giants of Circadian Biology Win Nobel Prize
Catherine Offord | Oct 2, 2017
The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.
Mammals May Have a 12-Hour Clock
Mammals May Have a 12-Hour Clock
Ashley Yeager | Jun 6, 2017
Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.
Mouse Livers Grow and Shrink Daily
Mouse Livers Grow and Shrink Daily
Abby Olena | May 4, 2017
Feeding-fasting rhythms and light-dark cycles direct regular changes in organ and cell size, as well as ribosome number and protein levels.
Clock Gene Mutation Leads to “Night Owl” Behavior
Clock Gene Mutation Leads to “Night Owl” Behavior
Diana Kwon | Apr 9, 2017
Scientists identify a mutation in the CRY1 gene in people with abnormal sleeping patterns.