In Drosophila, the tissue is more permeable to drugs at night, offering a possible explanation for why some medicines work better at certain times of day.

Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

Young talks with The Scientist about studying circadian rhythms in fruit flies, the applications of his work beyond Drosophila, and winning the prize. 

A basic curiosity about how life works led the Brandeis University molecular biologist to discover how our bodies keep time. 

The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.

Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.

Feeding-fasting rhythms and light-dark cycles direct regular changes in organ and cell size, as well as ribosome number and protein levels.

Scientists identify a mutation in the CRY1 gene in people with abnormal sleeping patterns.

Across many diseases, taking medication at specific times of day may make the therapy more effective.