A New Way to Establish Cause and Effect in Epidemiology?
A New Way to Establish Cause and Effect in Epidemiology?
A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.
A New Way to Establish Cause and Effect in Epidemiology?
A New Way to Establish Cause and Effect in Epidemiology?

A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.

A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.

clinical trial design
Interactive: Biomarkers in Blood Provide a Window into the Brain
Interactive: Biomarkers in Blood Provide a Window into the Brain
Shawna Williams | Dec 1, 2019
A look at some of the circulating molecules that may indicate various Alzheimer’s pathologies and serve as the bases of noninvasive tests for the disease.
The Hunt for a Blood Test for Alzheimer’s Disease
The Hunt for a Blood Test for Alzheimer’s Disease
Shawna Williams | Dec 1, 2019
Researchers hope circulating biomarkers will enable earlier detection and better monitoring of the neurodegenerative disorder—and perhaps help usher in new treatments.
Industry Partners Extensively Involved in Trials They Fund
Industry Partners Extensively Involved in Trials They Fund
Catherine Offord | Oct 5, 2018
A new study suggests that sponsors downplay their influence when reporting trials carried out in collaboration with academic researchers.
Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy
Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy
John D. Loike and Jennifer Miller | Feb 1, 2017
What can be done to lower development costs and drug prices?
Opinion: Why Most TBI Studies Fail
Opinion: Why Most TBI Studies Fail
Donald Stein | Feb 24, 2016
Thoughts on how to redesign clinical trials for traumatic brain injury
NCI Gets Personal
NCI Gets Personal
Bob Grant | Jun 2, 2015
The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.
Clinical Matchmaker
Clinical Matchmaker
Kate Yandell | Jun 1, 2015
Enrolling the right patient population could be key to a successful clinical trial.