Artist’s rendering of the protein synthesis process, in which a tRNA molecules carry amino acids to a ribosome that’s decoding a strand of mRNA.
Screen of 250,000 Species Reveals Tweaks to Genetic Code
A massive screen of bacterial and archaeal genomes revealed five previously unknown instances where an organism uses an alternate code to translate genetic blueprints into proteins.
ABOVE: © ISTOCK.COM, SELVANEGRA
Screen of 250,000 Species Reveals Tweaks to Genetic Code
Screen of 250,000 Species Reveals Tweaks to Genetic Code

A massive screen of bacterial and archaeal genomes revealed five previously unknown instances where an organism uses an alternate code to translate genetic blueprints into proteins.

A massive screen of bacterial and archaeal genomes revealed five previously unknown instances where an organism uses an alternate code to translate genetic blueprints into proteins.

ABOVE: © ISTOCK.COM, SELVANEGRA

codons

Most Extensive Synthetic Genome Project to Date
Ashley P. Taylor | May 16, 2019
Study shows the viability of bacteria with human-made, recoded DNA.
Protozoans Found With No Dedicated Stop Codons
Karen Zusi | Oct 1, 2016
Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.
Ciliates Are Genetic-Code Deviants
Karen Zusi | Sep 30, 2016
Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.
Streamlining the E. coli Genetic Code
Karen Zusi | Aug 18, 2016
Scientists design a bacterial genome with only 57 codons.
Reducing Repetition While Building Biopolymers
Kate Yandell | Jan 11, 2016
A free algorithm helps synthetic biologists decide which codons to use to encode repetitive proteins using the least-repetitive DNA sequence possible.
Week in Review: May 19–23
Tracy Vence | May 23, 2014
Sperm-sex–sensing sows; blocking a pain receptor extends lifespan in mice; stop codons can code for amino acids; exploring the tumor exome
When Stop Means Go
Ruth Williams | May 22, 2014
A survey of trillions of base pairs of microbial DNA reveals a considerable degree of stop codon reassignment.
Recoding Life
Laasya Samhita | Jan 2, 2014
Rewriting the genetic code can lead to a better understanding of how living cells work, and spawn new biotechnological applications.
Pioneer DNA Researcher Dies
Jef Akst | Oct 2, 2012
Leonard Lerman, who helped elucidate the process from gene to protein, passed away last month at age 87.
Going Strong at 75
Horace Freeland Judson | Mar 17, 2002
Roger Kornberg, one of Arthur's boys, has a Sydney Brenner story. We all do, but his is more telling than most.