News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
Protozoans Found With No Dedicated Stop Codons
Karen Zusi | Oct 1, 2016
Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.
Ciliates Are Genetic-Code Deviants
Karen Zusi | Sep 30, 2016
Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.
Karen Zusi | Aug 18, 2016
Scientists design a bacterial genome with only 57 codons.
Reducing Repetition While Building Biopolymers
Kate Yandell | Jan 11, 2016
A free algorithm helps synthetic biologists decide which codons to use to encode repetitive proteins using the least-repetitive DNA sequence possible.
Week in Review: May 19–23
Tracy Vence | May 23, 2014
Sperm-sex–sensing sows; blocking a pain receptor extends lifespan in mice; stop codons can code for amino acids; exploring the tumor exome
When Stop Means Go
Ruth Williams | May 22, 2014
A survey of trillions of base pairs of microbial DNA reveals a considerable degree of stop codon reassignment.
Laasya Samhita | Jan 2, 2014
Rewriting the genetic code can lead to a better understanding of how living cells work, and spawn new biotechnological applications.
Pioneer DNA Researcher Dies
Jef Akst | Oct 2, 2012
Leonard Lerman, who helped elucidate the process from gene to protein, passed away last month at age 87.