cryo-electron microscopy

From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.

Researchers highlight protein structure considerations for designing inhibitors that target familial Parkinson’s disease mutations.

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

Cryo-electron tomography reveals how Salmonella sets up physical interactions with host cells.

Modified cryogenic electron microscopy can analyze viral structures better than ever before.

Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson.