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3D illustration of p53 bound to DNA
One Protein to Rule Them All
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
One Protein to Rule Them All
One Protein to Rule Them All

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.

cryo-electron microscopy

 Dive into Cryo-EM’s History, Milestones, and Insights.
Cryo-EM: Building on a History of Invention and Innovation
Thermo Fisher Scientific | Aug 2, 2023 | 1 min read
From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.
3D rendered medical illustration of neurons containing Lewy bodies (small red spheres), accumulated proteins in brain cells that cause degeneration and are linked to Parkinson’s disease.
The Bigger Protein Picture of Designing Parkinson’s Therapeutics
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers highlight protein structure considerations for designing inhibitors that target familial Parkinson’s disease mutations.
Artist’s rendition of the molecular structure of a ribosome (blue and purple) as it produces a polypeptide chain (red) from an mRNA template (orange and gray), with tRNA molecules (dark purple) shuttling amino acids.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
Dan Robitzski | Dec 15, 2022 | 4 min read
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.
Neurons traversing the brain with an area of red neurodegeneration
LabTalk Podcast - The New Era of Neurodegeneration Research
The Scientist | Sep 20, 2022 | 1 min read
Erdem Gültekin Tamgüney discusses the future of neurodegeneration research and his work exploring the link between stroke and Parkinson’s disease.
Image of the Day: First Contact
Catherine Offord | Oct 11, 2018 | 1 min read
Cryo-electron tomography reveals how Salmonella sets up physical interactions with host cells.
Image of the Day: Viral Vision
Sukanya Charuchandra | Sep 18, 2018 | 1 min read
Modified cryogenic electron microscopy can analyze viral structures better than ever before.
Scientists Who Developed Cryo-Electron Microscopy Win Nobel Prize
Diana Kwon | Oct 4, 2017 | 3 min read
Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 
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