dendritic cells

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.

Annie Curtis’s research team revealed how circadian rhythm-regulated mitochondrial metabolism drives dendritic cell antigen presentation activity.

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.

Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.

The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response.

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

Scientists show that an influx of noradrenaline can halt immune cells in mice.

Cancer therapies could potentially be more effective if their development took into account the cells that give rise to tumor-fighting cells.

Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.

Injecting immunostimulants directly into the tumor is not a new strategy to stimulate the immune system, but the approach has seen a surge of interest in recent years.

A video captures T cells learning to recognize cells from the body that shouldn’t be attacked.

The Mount Sinai oncologist studies innate immune cells with the goal of designing novel immunotherapies, including cancer vaccines.

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.