More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

Scientists show that an influx of noradrenaline can halt immune cells in mice.

Cancer therapies could potentially be more effective if their development took into account the cells that give rise to tumor-fighting cells.

Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.

Injecting immunostimulants directly into the tumor is not a new strategy to stimulate the immune system, but the approach has seen a surge of interest in recent years.

A video captures T cells learning to recognize cells from the body that shouldn’t be attacked.

The Mount Sinai oncologist studies innate immune cells with the goal of designing novel immunotherapies, including cancer vaccines.

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

Researchers document the diverse roles of immune cells in neuronal health and disease.

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

Vaccination via tiny microneedles elicits a powerful immune response in the skin.