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Blue glowing neuronal projections
Silent Synapses May Provide Plasticity in Adulthood
Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.
Silent Synapses May Provide Plasticity in Adulthood
Silent Synapses May Provide Plasticity in Adulthood

Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.

Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.

dendritic cells
Artist’s rendition of light blue monkeypox viruses in front of a black background.
FDA To Stretch Monkeypox Vaccine Supply via Intradermal Injection
Shafaq Zia | Aug 12, 2022 | 4 min read
The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.
Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
cartoon of a scientist holding a magnifying glass up to test tubes of blood
How the Second mRNA Vaccine Bolsters Immunity
Annie Melchor | Jul 23, 2021 | 6 min read
A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response.
Illustration of the BCG vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021 | 3 min read
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
Stress Paralyzes Immune Cells
Emma Yasinski | Jul 1, 2021 | 2 min read
Scientists show that an influx of noradrenaline can halt immune cells in mice.
LabTalk Podcast - Predicting the Immune Response with Single-Cell Analysis: Autoimmunity, Vaccination, and COVID-19
The Scientist Creative Services Team and 10x Genomics | Mar 31, 2021 | 1 min read
Researchers identify signatures that predict how a person will respond to an immune system stimulus.
The Scientist's LabTalk Podcast - Episode 1
The Scientist Creative Services Team | Sep 11, 2020 | 1 min read
Myeloid Cells in Cancer and Science Advocacy: A Conversation with Dr. Miriam Merad
Infographic: How Immunotherapy Could Boost Stem-Like T Cells
Daniel E. Speiser and Werner Held | Jul 13, 2020 | 3 min read
Cancer therapies could potentially be more effective if their development took into account the cells that give rise to tumor-fighting cells.
Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Daniel E. Speiser and Werner Held | Jul 13, 2020 | 9 min read
Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.
dendritic cell t cell immunology cancer immunotherapy in situ vaccine
In Situ Vaccination: A Cancer Treatment a Century in the Making
Emma Yasinski | Jul 25, 2019 | 6 min read
Injecting immunostimulants directly into the tumor is not a new strategy to stimulate the immune system, but the approach has seen a surge of interest in recent years.
T cells learning training immune system
Image of the Day: Training Day
Chia-Yi Hou | May 24, 2019 | 1 min read
A video captures T cells learning to recognize cells from the body that shouldn’t be attacked.
Miriam Merad
Cancer Vaxxer: A Profile of Miriam Merad
Anna Azvolinsky | Apr 1, 2019 | 8 min read
The Mount Sinai oncologist studies innate immune cells with the goal of designing novel immunotherapies, including cancer vaccines.
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018 | 2 min read
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Researchers Uncover Previously Unknown Immune Cell Subtypes
Aggie Mika | Jul 16, 2017 | 2 min read
Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.
Fetal Immune System Operational by Second Trimester
Abby Olena, PhD | Jun 14, 2017 | 3 min read
Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.
Immunity in the Brain
Amanda B. Keener | Oct 31, 2016 | 2 min read
Researchers document the diverse roles of immune cells in neuronal health and disease.
Personalized Cancer Vaccines
Anna Azvolinsky | Apr 2, 2015 | 3 min read
A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 
Next Generation: Painless Vaccine Patch
Megan Scudellari | Apr 2, 2012 | 3 min read
Vaccination via tiny microneedles elicits a powerful immune response in the skin.
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