Image of a pregnant woman holding her belly with blurred plastic bottles in the background.

| 5 min read

A Common Plastic Additive Harms DNA and Chromosomes

Plastic chemicals may harm DNA, as new research reveals how additives disrupt nematode egg formation, suggesting risks to human reproductive health.

3D illustration of purple neurons.

| 4 min read

An Immune Mechanism Maintains Memory

A younger-looking mouse next to an older-looking one

| 4 min read

Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice

DNA double-stranded breaks

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 2 min read

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 3 min read

literature infographic dna repair

Without This Enzyme, Insertions Thrive in the Yeast Genome

Katarina Zimmer | | 3 min read

the literature infographic dna repairing

Infographic: How Stray DNA Can Land in Double-Strand Breaks

Katarina Zimmer | | 1 min read

Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine

Catherine Offord | | 9 min read

Brain Activity Breaks DNA

Sabrina Richards | | 3 min read

Page 1 of 1 - 9 Total Items

Trending

Image of colorful microplastics against a black background.

Microplastics Build Up in Human Organs, Especially the Brain

New research uncovered an alarming accumulation of plastic particles in human brains, raising concerns about their potential role in neurodegenerative disease.

Cleaning supplies in a basket against a neutral background.

How Bacteria Outsmart Disinfectants

Disinfectants induce oxidative damage in bacteria, but a single mutation triggers the expression of genes that help the microbe survive.

Image of a DNA strand with a magnifying glass hovering over one section (left). A sweating man lifts his arm and emits body odor with a callout depicting that he has yellow colored earwax (right).

How Are Earwax and Body Odor Linked?

A single gene controls earwax and body odor, shaping one’s unique scent through microbes.

A white mouse running on an exercise wheel in its cage.

How the Brain Chooses to Eat or Exercise

Neurons that secrete the neuropeptide orexin help mice decide between exercise and snacking.

Multimedia

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

In this webinar, Daryl Cole will share insights into the high-throughput screening and analysis of antibody binding and functional characterization.

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Learn how to overcome the challenges of viral transduction workflows.

3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.

February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

View this Issue

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

In this webinar, Daryl Cole will share insights into the high-throughput screening and analysis of antibody binding and functional characterization.

Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

In this webinar, Ethan Shelkey and Aurita Menezes will highlight key aspects in the design of cell-based assays.

An illustration of animal and tree silhouettes.

From Water Bears to Grizzly Bears: Unusual Animal Models

Discover how alternative animal models provide new perspectives on physiological and biochemical processes.

Sex Differences in Neurological Research

Sex Differences in Neurological Research

Experts from the Women’s Brain Foundation and bit.bio will explore the importance of sex-specific in vitro models for neurological research and drug discovery.

Products

Product News

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide

Multiomics platform streamlines workflows and provides real-time insights, optimizing resource usage and ensuring smooth, data-driven operations

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Learn how to overcome the challenges of viral transduction workflows.

Inventia Life Science Launches RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

Inventia Life Science, an innovator in 3D cell culture technologies, announces the launch of RASTRUM™ Allegro, a groundbreaking advancement in 3D cell culture technology designed to accelerate drug discovery and disease research with unprecedented scalability, reproducibility, and efficiency.

An illustration of differently shaped viruses.

Detecting Novel Viruses Using a Comprehensive Enrichment Panel

Learn how a target enrichment approach improves the discovery and characterization of viral pathogens.

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