A close-up of a computer-generated tardigrade.
| 3 min read
Boosting cells with a tardigrade protein reduced DNA damage after radiation, offering potential protection for healthy tissue during cancer treatment.

DNA double-stranded breaks

A younger-looking mouse next to an older-looking one

Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

literature infographic dna repair

Without This Enzyme, Insertions Thrive in the Yeast Genome

the literature infographic dna repairing

Infographic: How Stray DNA Can Land in Double-Strand Breaks

Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine

Brain Activity Breaks DNA

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An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
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Thermo Scientific X and S Series General Purpose Centrifuges

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Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

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Thermo Scientific X and S Series General Purpose Centrifuges

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VANTAstar Flexible microplate reader with simplified workflows

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