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Blue DNA double helix breaking apart.
Keeping Telomeres in Their Places
New research reveals how cells prevent telomerase from meddling with double-stranded breaks.
Keeping Telomeres in Their Places
Keeping Telomeres in Their Places

New research reveals how cells prevent telomerase from meddling with double-stranded breaks.

New research reveals how cells prevent telomerase from meddling with double-stranded breaks.

double-strand breaks

A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
Promoting homology-directed repair (HDR) in CRISPR applications
Improving CRISPR Homology-Directed Repair (HDR) Rates
Integrated DNA Technologies (IDT) | Jan 31, 2022 | 1 min read
Improved reagents and careful donor design boost HDR rates for genome engineering.
illustration of a broken DNA strand
DNA Damage Makes Zebrafish Sleepy
Sophie Fessl, PhD | Nov 18, 2021 | 4 min read
Buildup of a DNA-repair protein in brain cells spurs shut-eye in the fish, a study finds, and similar results in mice suggest the mechanism is widespread in animals.
literature infographic dna repair
Without This Enzyme, Insertions Thrive in the Yeast Genome
Katarina Zimmer | Mar 1, 2019 | 3 min read
A study underscores the importance of Dna2 in maintaining the integrity of the genetic code.
the literature infographic dna repairing
Infographic: How Stray DNA Can Land in Double-Strand Breaks
Katarina Zimmer | Mar 1, 2019 | 1 min read
A study on yeast illuminates how insertions may occur.
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017 | 8 min read
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
Cranking Out New Models
Kate Yandell | May 6, 2013 | 2 min read
Scientists make mice strains with multiple mutations in less than a month without using embryonic stem cells.
Why Women’s Eggs Don’t Last
Kate Yandell | Feb 13, 2013 | 3 min read
As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.
Daniel Durocher: Change is Good
Kerry Grens | Jul 1, 2012 | 3 min read
Senior Investigator, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada. Age 40
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