Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies

A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.

A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.

Drosophila melanogaster
Artist’s rendition of bright blue microbes among intestinal lining
Study Links Depression with High Levels of an Amino Acid
Dan Robitzski | Jun 14, 2022
Experiments in animals and observations in humans suggest that the amount of proline circulating in one’s plasma has a strong association with depression severity.
A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.
Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut
Natalia Mesa | May 18, 2022
Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.
Photo of Ana Marija Jakšic
Ana Marija Jakšić Shapes Fruit Fly Brains
Chloe Tenn | Apr 18, 2022
The Swiss Federal Institute of Technology Lausanne evolutionary neurobiologist is using Drosophila to investigate how organisms adapt to novel environments.
Drosophila melanogaster on cactus leaf
Fruit Flies Evolve in Time with the Seasons: Study
Natalia Mesa | Mar 17, 2022
Researchers find that evolution can operate on extraordinarily fast timescales.
Illustration of gray bacteriophages approaching and infecting a red and orange bacteria that has multiple fimbria protruding from it.
Bacteria-Infecting Viruses in Gut Microbiome Linked to Cognition
Dan Robitzski | Feb 16, 2022
Research in mice and flies suggests that bacteriophages, including those found in dairy foods, may have an influence on an animals’ ability to learn and remember information.
Image of fruit fly epithelial cells (pseudo colored in this micrograph)
Epithelial Cell Signaling Helps Maintain Tissue Integrity
Annie Melchor | Nov 1, 2021
Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.
A multicolored section of a fruit fly brain
Tumors Disrupt the Blood-Brain Barrier at a Distance
Abby Olena | Sep 9, 2021
Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.
A close-up of a fruit fly head with antenna clearly visible in front of its red eyes
Bacterial Infections Disrupt Flies’ Sense of Smell
Abby Olena | Jul 21, 2021
The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.
Insects Pass Antiviral Immunity to Offspring
Abby Olena | Dec 17, 2020
In both Drosophila and mosquitoes, protection lasts for generations following a single maternal exposure to positive-sense single-stranded RNA viruses.
fruit fly drosophila melanogaster sperm sex peptide memory reproduction
Sex Promotes Lasting Memories in Female Flies
Ruth Williams | Nov 20, 2019
A protein present in the ejaculate of male fruit flies activates long-term memory formation in the brains of their female partners.
Image of the Day: Poison Tolerance
Emily Makowski | Oct 3, 2019
Genetically engineered Drosophila withstand toxins common in monarch butterflies’ diet.
drosophila eye development retina fruit fly imaginal disc
Image of the Day: Fly Eye
Chia-Yi Hou | Jul 16, 2019
See a developing Drosophila eye.
fruit fly
Artificially Intelligent Tools Capture Animal Movement
Carolyn Wilke | May 1, 2019
Algorithms for motion capture help neuroscientists dig into the question of how the brain produces behavior.
Image of the Day: In the Eye of a Fly
Carolyn Wilke | Feb 26, 2019
A missing microRNA leads to degenerating neurons and blindness in a fruit fly.
Image of the Day: Gut Bomb
Catherine Offord | Dec 10, 2018
Microbial species living in a fruit fly gut interact with one another—and influence the insect’s health and longevity in the process.
Fruit Fly Geneticist Bruce Baker Dies
Diana Kwon | Jul 30, 2018
The Stanford University professor was known for his work on sex determination and courtship in flies.
Fruit Fly Males Woo Females with Three Songs, Not Two
Abby Olena | Jul 26, 2018
Researchers show that Drosophila melanogaster males are capable of producing more modes of courtship song with their wings than previously thought.
Fly’s Blood-Brain Barrier Has Circadian Rhythms
Abby Olena | Mar 8, 2018
In Drosophila, the tissue is more permeable to drugs at night, offering a possible explanation for why some medicines work better at certain times of day.
3-D–Printed Ethoscopes Lower Barriers to Large-Scale Fly Behavior Studies
Ruth Williams | Jan 1, 2018
The DIY devices collect data and enable light stimulation, chamber agitation, and gas infusion.