fingertips with pills on them
Over-the-Counter Antihistamines Could Help Against Cancer
The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.
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Over-the-Counter Antihistamines Could Help Against Cancer
Over-the-Counter Antihistamines Could Help Against Cancer

The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.

The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.

ABOVE: ©ISTOCK.COM, ANEDUARD

drug resistance

illustration of colorful microbes inside a person's stomach and intestines
How Commensal Gut Bacteria Keep Pathogens in Check
Alejandra Manjarrez | Oct 14, 2021
Recent studies describe how resident microbiota appear to outcompete unwelcome visitors, either with superior weaponry or by guzzling up local resources.  
illustration showing a microscopic view of C. auris, with clusters of round balls connected by filaments
CDC Warns of Person-to-Person Transmission of Resistant Fungus
Shawna Williams | Jul 26, 2021
In a first, patients who hadn’t been treated with antifungals were found to carry Candida auris impervious to all three available classes of the drugs.
Evangelos Kiskinis describes how the patient-derived iPSCs model of epilepsy help predict drug resistance.
The Scientist Speaks - Modeling Epilepsy in a Dish Using Patient-Derived iPSCs
Sejal Davla, PhD | Jan 28, 2022
Evangelos Kiskinis describes how the patient-derived iPSCs model of epilepsy help predict drug resistance.
A false-colored micrograph showing swirls of yellow, red, and magenta cells
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl | Jul 16, 2021
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
Infographic: Researchers Take Aim at Cancer Evolution
Catherine Offord | Apr 1, 2020
Strategies to trick, manipulate, and direct the evolution of tumors
The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells
LabTalk Podcast - Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers
The Scientist Creative Services Team, 10x Genomics | Nov 23, 2021
The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells.
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
Cancer Cells Increase DNA Mutations to Evade Treatment
Abby Olena | Nov 7, 2019
Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.
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The Scientist Speaks - Homing in on New Anticancer Targets 
Sejal Davla, PhD | Sep 28, 2021
Jason Sheltzer discusses cancer mechanisms leading to drug resistance and new approaches to find drug targets.
First New Tuberculosis Drug Approved in 50 Years
Jef Akst | Aug 15, 2019
The US Food and Drug Administration green lights a therapy for an extreme form of multidrug resistant TB.
fecal matter transplant FDA suspend halt clinical trials patient dies died antibiotic resistance drug resistant
FDA Suspends Clinical Trials Involving Fecal Transplants
Chia-Yi Hou | Jun 14, 2019
The agency issued a safety warning after two patients contracted antibiotic-resistant infections and one of the patients died.
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Understanding Our Enemies: Identifying Mechanisms of Antibiotic Resistance
The Scientist Creative Services Team | Aug 3, 2021
Researchers sample and sequence bacteria from biological and environmental sources to learn how to overcome selective pressure
christina cuomo candida auris
Q&A: What to Know About the Drug-Resistant Fungus, Candida auris
Emma Yasinski | Apr 18, 2019
Fungal researcher Christina Cuomo discusses the spread of infections plaguing hospitals across the world.
malaria infographic
Infographic: Fighting Malaria Drug Resistance
Natalie Slivinski | Mar 1, 2019
The parasite that causes malaria has evolved to evade many of the drugs that researchers have developed to fight the tropical disease.
A Connected Community: The Rise of Microbiome Research
The Scientist Creative Services Team | Apr 30, 2021
Explore how microbes shape health, disease, and the world beyond
malaria feature
Are We Headed for a New Era of Malaria Drug Resistance?
Natalie Slivinski | Mar 1, 2019
Plasmodium falciparum has shown an ability to evade everything we throw at it, most recently artemisinin-based combination therapies, today’s front-line treatment.
Image of the Day: Tumor Organoids
The Scientist Staff, The Scientist Staff | Apr 11, 2018
Miniature versions of bladder cancers could help physicians identify personalized treatment options for patients.
Checking Checkpoints for Treating Cancer
The Scientist Creative Services Team | Mar 31, 2021
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
Mutant RAS Proteins Team Up for Oncogenicity
Jim Daley | Apr 1, 2018
Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.