drug resistance

In this webinar, Pinaki Bose and Fei Chen will discuss how scientists use spatial biology techniques to study the tumor microenvironment.

Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.

Overcome drug resistance by targeting host proteins.

Evangelos Kiskinis describes how the patient-derived iPSCs model of epilepsy help predict drug resistance.

The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.

The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells.

Recent studies describe how resident microbiota appear to outcompete unwelcome visitors, either with superior weaponry or by guzzling up local resources.  

Jason Sheltzer discusses cancer mechanisms leading to drug resistance and new approaches to find drug targets.

Researchers sample and sequence bacteria from biological and environmental sources to learn how to overcome selective pressure

In a first, patients who hadn’t been treated with antifungals were found to carry Candida auris impervious to all three available classes of the drugs.

Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.

Explore how microbes shape health, disease, and the world beyond

Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.

A tumor metabolome panel identifies altered cell states that lead to drug tolerance.

Discover how scientists use multi-omic approaches to identify functional changes that lead to cancer cell drug resistance and devise new treatment strategies.

Researchers Jason Gill and Paul Turner will discuss their work on bacteriophage therapy to treat drug resistant bacterial infections.

Download this research summary to learn about how single-cell proteomics and metabolomics methods unlock drug resistance mechanisms!

Strategies to trick, manipulate, and direct the evolution of tumors