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AI mice in labs
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals
Machine learning could be the key to reducing the use of animals in experiments.
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals

Machine learning could be the key to reducing the use of animals in experiments.

Machine learning could be the key to reducing the use of animals in experiments.

drug toxicity
Detecting Subvisible Particles in Protein Therapeutics
The Scientist Creative Services Team in collaboration with Yokogawa Fluid Imaging Technologies | Feb 16, 2021 | 3 min read
New flow imaging microscopy technology visualizes a broad range of subvisible particles hidden in therapeutic suspensions.  
Software-Based Chemical Screen Could Minimize Animal Testing
Anna Azvolinsky | Jul 13, 2018 | 4 min read
Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.
Severe Toxicity Reported in High-Dose AAV Gene Therapy in Animals
Jim Daley | Jan 31, 2018 | 2 min read
Biotech stocks fell in response to the news. 
Animal-Free Toxicity Testing
Anna Azvolinsky | Jan 26, 2016 | 4 min read
Scientists debut a system that can quickly test the toxicity of thousands of compounds in vitro.
Battling the Bulge
Bob Grant | Nov 1, 2015 | 6 min read
Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.
Epigenetic Cancer Therapy Clears Phase I
Tracy Vence | Apr 7, 2014 | 2 min read
Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.
Kerfuffle Over Marijuana Claim
Bob Grant | Aug 20, 2013 | 2 min read
A pro-pot group airs an ad stating marijuana is “less toxic” than alcohol, but a federal science agency disputes the assertion.
The Elixir Tragedy, 1937
Jef Akst | Jun 1, 2013 | 3 min read
A mass poisoning of 105 patients treated with an untested medication spurred Congress to empower the US Food and Drug Administration to monitor drug safety.
Spinning Clinical Trials
Dan Cossins | Jan 16, 2013 | 1 min read
Results of breast cancer drug trials are regularly spun to conceal bias and make the drugs seem more effective or less toxic than they really are.
A Dime a Dozen
Megan Scudellari | Jan 1, 2013 | 7 min read
Affordable diagnostic tests tackle the world’s most pressing health problems.
Stemming the Toxic Tide
Kelly Rae Chi | Sep 1, 2012 | 8 min read
How to screen for toxicity using stem cells
Tissue on Chips Galore
Edyta Zielinska | Jul 26, 2012 | 1 min read
The National Institutes of Health will fund 17 projects developing lab-on-a-chip applications to improve drug screening.
Lab Rats Need Better Diets
Hayley Dunning | Jul 18, 2012 | 1 min read
Rodents fed all-you-can-eat diets may be skewing experimental results.
An Antidote for Cocaine Overdose?
Cristina Luiggi | Apr 19, 2012 | 1 min read
A novel antibody with a powerful affinity for cocaine shows promise in reversing the deadly effects of an overdose.
Avoiding Animal Testing
Andrew Rowan | Dec 1, 2011 | 3 min read
Advances in cell-culture technologies are paving the way to the complete elimination of animals from the laboratory.
New Drug Toxicity Chip
Jef Akst | Sep 19, 2011 | 1 min read
The NIH, FDA, and DARPA are teaming up to develop a chip to test drug toxicities as one of the first projects of the NIH's new translational research center.
Regulating the Humanized
Bob Grant | Jul 25, 2011 | 1 min read
A UK panel puts forth guidelines for research that use experimental animals harboring human cells and tissues.
Humanized Mice Make Better Models
Jef Akst | Jul 13, 2011 | 2 min read
Mice with miniature human livers more accurately test a drug’s toxic side effects.
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