Neurons in all sorts of different colors, some glowing
How Fear Restructures the Mouse Brain
By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.
How Fear Restructures the Mouse Brain
How Fear Restructures the Mouse Brain

By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.

By combining deep learning and electron microscopy, researchers now have a more detailed understanding of how fear changes the brain.

electron microscopy
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
An illustration of a flask of bacteria, a weighted microscope slide, and two bacteria exchanging materials via nanotubes.
Infographic: Sources of Variation in Bacterial Nanotube Studies
Sruthi S. Balakrishnan | Jun 1, 2021
Differences in how researchers prepare and image samples can lead to discrepancies in their results.
Form Determines Function: Insights from Structural Biology
The Scientist Creative Services Team
Researchers use diverse tools to analyze protein structures.
Coronavirus Closeup, 1964
Ashley Yeager | Sep 1, 2020
Electron microscopy revealed that a deadly disease of birds was not a form of flu, but a different type of virus entirely.
Coronavirus-Infected Cells Grow Filopodia
Shawna Williams | Jun 30, 2020
SARS-CoV-2 causes cells to put out projections that spread the virus, a study finds.
Transforming Virology Research with Cryo-EM
The Scientist Creative Services Team and Thermo Fisher Scientific
Explore what researchers can do with Cryo-EM
Image of the Day: Coronavirus Under the Scope
Amy Schleunes | Feb 17, 2020
The National Institute of Allergy and Infectious Diseases releases a series of images that offer a close up look at the novel coronavirus SARS-CoV-2.
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Aaron Klug, Developer of Crystallographic Electron Microscopy, Dies
Ashley P. Taylor | Nov 26, 2018
The chemist and biophysicist won a Nobel prize for the development of a technique to probe the structures of nucleotide-protein complexes.
Image of the Day: Feather Mites
The Scientist Staff and The Scientist Staff | Feb 19, 2018
Researchers used scanning electron microscopy to peer at bugs on several hummingbird species.
Image of the Day: Beetle Penis 
The Scientist Staff and The Scientist Staff | Dec 22, 2017
Scientists look to a leaf beetle’s genitals for lessons on improving catheter strength.  
Scientists Who Developed Cryo-Electron Microscopy Win Nobel Prize
Diana Kwon | Oct 4, 2017
Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 
Entire Fruit Fly Brain Imaged with Electron Microscopy
Ashley Yeager | May 31, 2017
Synaptic connections and a new neuron type emerge in high-res images, which hold promise for mapping the complete connectome.
Doors and Pores
Mary Beth Aberlin | Dec 1, 2016
The awesome architecture of the gateways to the nucleus
Electron Micrographs Get a Dash of Color
Ben Andrew Henry | Nov 3, 2016
A new technique creates colorful stains that label proteins and cellular structures at higher resolution than ever before possible. 
Microscopy’s Growth Through the Years
Jenny Rood | Oct 1, 2016
From confocal fluorescence microscopy to super-resolution and live 3-D imaging, microscopes have changed rapidly since 1986.
First Glimpse at Infectious Prion Shape
Abby Olena | Sep 8, 2016
The preliminary structure of the misfolded protein that causes mad cow disease and Creutzfeldt-Jakob disease looks like a coiled mattress spring.
Thermo Fisher to Acquire FEI
Tracy Vence | Jun 1, 2016
In a $4.2 billion deal, the science equipment giant is buying the Hillsboro, Oregon-based electron microscope maker.
Zika Up Close
Anna Azvolinsky | Mar 31, 2016
A detailed structure of the pathogen highlights its similarities to—and one major difference from—other flaviviruses.