endoplasmic reticulum

Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.

Various microbes, including several human pathogens, hijack the cell’s skeleton, membranes, and protein-making machinery to make themselves at home.

The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

The ribosome-associated organelle consists of tightly packed tubes, not flat sheets as previously believed, according to new super-resolution microscopy images.

Associate Professor, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder. Age: 43

Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 

Electron microscopy led to the first identification of what would later be known as ribosomes.

Nobel Laureate Christian de Duve discusses the impact of George Palade’s work on ribosomes.

There’s beauty in a cell’s marriage of structure and function.

Membrane twists connect stacked endoplasmic reticulum sheets.

A chemical prevalent in the bear gallbladder abates a cellular stress response and stalls the progression of type 1 diabetes in rodents.

The first electron microscope to peer into an intact cell ushers in the new field of cell biology.

Editor's choice in cell biology

Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.

Editor's Choice in Cell Biology