New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly
Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.
New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

endoplasmic reticulum
Structural Details of Endoplasmic Reticulum Revealed
Structural Details of Endoplasmic Reticulum Revealed
Jef Akst | Oct 28, 2016
The ribosome-associated organelle consists of tightly packed tubes, not flat sheets as previously believed, according to new super-resolution microscopy images.
Gia Voeltz: Cellular Cartographer
Gia Voeltz: Cellular Cartographer
Karen Zusi | Dec 1, 2015
Associate Professor, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder. Age: 43
Targeted ER Breakdown
Targeted ER Breakdown
Ashley P. Taylor | Jun 16, 2015
Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 
Palade Particles, 1955
Palade Particles, 1955
Kerry Grens | Feb 1, 2014
Electron microscopy led to the first identification of what would later be known as ribosomes.
Palade and His Particles
Palade and His Particles
Kerry Grens | Jan 31, 2014
Nobel Laureate Christian de Duve discusses the impact of George Palade’s work on ribosomes.
Intracellular Spirals
Intracellular Spirals
Kate Yandell | Dec 1, 2013
Membrane twists connect stacked endoplasmic reticulum sheets.
Organelle Architecture
Organelle Architecture
Mary Beth Aberlin | Dec 1, 2013
There’s beauty in a cell’s marriage of structure and function.
Bile Compound Prevents Diabetes in Mice
Bile Compound Prevents Diabetes in Mice
Kerry Grens | Nov 14, 2013
A chemical prevalent in the bear gallbladder abates a cellular stress response and stalls the progression of type 1 diabetes in rodents.
The Subcellular World Revealed, 1945
Cristina Luiggi | Mar 1, 2012
The first electron microscope to peer into an intact cell ushers in the new field of cell biology.
Give Me a Hug
Tia Ghose | Feb 1, 2012
Editor's choice in cell biology
The Enigmatic Membrane
Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | Feb 1, 2012
Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.
Traffic Cops
Jessica P. Johnson | Oct 1, 2011
Editor's Choice in Cell Biology