A headshot of Clinton Cave
Clinton Cave Investigates How Brain Cells Communicate
The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.
Clinton Cave Investigates How Brain Cells Communicate
Clinton Cave Investigates How Brain Cells Communicate

The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.

The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.

enzymes
Artist’s 3D rendering of malignant cancer cells, illustrated in pink, as it would appear under a scanning electron microscope.
Underdog Enzyme Likely Responsible for Mutations in Most Cancers
Sophie Fessl | Jul 28, 2022 | 3 min read
A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.
3D illustration showing neurons inside the brain
Experimental Pill to Treat Parkinson’s Is Safe, Trial Finds
Andy Carstens | Jun 10, 2022 | 2 min read
Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.
Enzymes Cutting Extracellular Matrix
An Introduction to Enzymes
The Scientist Creative Services Team | 1 min read
Discover how enzymes work and why they're an integral part of scientific laboratories.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 5+ min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
A micrograph of the prion-like state of a protein called Pus4
Protein Mediates Non-Genetic Inheritance of Growth Strategies
Catherine Offord | Jan 4, 2022 | 2 min read
An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.
ELISA tips and tricks
Technique Talk: ELISA Tips and Tricks
The Scientist Creative Services Team | 1 min read
Learn to optimize ELISA experiments in this workshop.
DNA
In Editing RNA, Researchers See Endless Possibilities
Christie Wilcox | Dec 1, 2021 | 5+ min read
RNA editing has been in DNA editing’s shadow for nearly a decade, but recent investments in the technology could bring it into the limelight.
Photograph of a brown laboratory mouse
Experiment Gone Awry Suggests Novel Way to Combat Hypoxia
Phil Jaekl | Oct 1, 2021 | 4 min read
While exploring suspended animation in mice, scientists discover how an enzyme can protect the brain from dangerously low levels of oxygen.
Extreme Biotech: Understanding Extremophile Biology to Impact Human Health
The Scientist Creative Services Team | 1 min read
Jaclyn Winter and Shiladitya DasSarma will discuss how they harness the unique biology of extremophiles for the discovery and development of new therapeutics.
Profile of old man wearing glasses, looking up to the left.
Edmond Fischer, Biochemist and Nobel Laureate, Dies at 101
Lisa Winter | Aug 31, 2021 | 2 min read
Fischer was recognized for his work with reversible protein phosphorylation.
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena | Aug 6, 2021 | 4 min read
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
Black and white image of Jean Wilson in an office, wearing a lab coat.
Endocrinologist Jean Wilson Dies at 88
Lisa Winter | Jun 24, 2021 | 2 min read
The University of Texas Southwestern professor’s research focused on the androgen hormones that cause male sexual differentiation and may also lead to prostate disease.
a white menstrual pad with pink and yellow spotting
Threads Embedded in Pads and Tampons Can Diagnose Yeast Infection
Emma Yasinski | Jun 15, 2021 | 3 min read
The material turns bright pink when it comes in contact with an enzyme produced by the fungus Candida albicans.
Infographic: Light Triggers Photocage Opening, Apoptosis Inhibition
Jef Akst | Jan 1, 2021 | 1 min read
Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.
Blood Transplants from Active Mice Give Brain Boost to Others
Lisa Winter | Jul 12, 2020 | 2 min read
The researchers behind the results propose that an exercise-induced protein in circulation is responsible for the benefits.
Infographic: Synthetases and the Evolution of Circulatory Systems
Amber Dance | Jun 1, 2020 | 5+ min read
Aminoacyl tRNA synthetases picked up new protein domains that participate in vasculature formation around the same time that organisms evolved key adaptations in the circulatory system.
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020 | 5+ min read
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.
Image of the Day: Coronavirus in 3D
Amy Schleunes | Mar 25, 2020 | 1 min read
At Bessy II, a synchrotron radiation facility in Berlin, scientists use X-rays to study the structure of SARS-CoV-2.
Image of the Day: Unusual ATP Synthase
Emily Makowski | Jan 8, 2020 | 2 min read
A single-celled organism has an energy-producing enzyme with unique features.