A woman getting out of bed next to an alarm clock. People with advanced sleep phase trait have early sleep onset and offset due to genetic mutations leading to shorter circadian period.

| 4 min read

The Genetic Variants Behind "Early Bird" Sleep Patterns

Identifying the mutations that underly unusual sleep traits can provide insights into the biology of sleep and circadian function in humans.

Petros Giannikopoulos (right) and Fyodor Urnov (left) stand in the lab where the on-demand CRISPR therapy was produced. They are both wearing blue shirts and glasses.

| 5 min read

Baby KJ’s Bespoke Gene Therapy Is a Masterclass in Scientific Collaboration

Diagram showing epigenome editing using DNA methylation tools and recombinant proteins to control gene expression in human cells.

| 10+ min read

A New Era of Epigenetic Medicines

genetic disease

Hands wearing blue gloves use scissors and forceps to cut DNA.

David Liu Wins 2025 Breakthrough Prize for Base Editing and Prime Editing

Hannah Thomasy, PhD | | 9 min read

A close-up image of two fruit flies. These fruit flies are useful models in studying genetic variations.

From Flies to Families: How a Gene Variant May Shield Against Seizures

Laura Tran, PhD | | 3 min read

An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

Charles River Laboratories, Inc.andThe Scientist | | 3 min read

iStock

Catch Me If You Can: Sequencing Screens for Rare Disease Genes

The Scientist | | 1 min read

The heart sections on the left present defects while the hearts on the right do not show defects.

Genetic Signatures of a Defective Heart

Mariella Bodemeier Loayza Careaga, PhD | | 4 min read

Keeping Kidneys Healthy with a Hand from AI

Aparna Nathan, PhD | | 3 min read

MRI images of brains from patients with epilepsy

Defending against Dravet

Aparna Nathan, PhD | | 3 min read

Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University

The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease

Niki Spahich, PhD | | 3 min read

Researchers in George Church’s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.

A Pioneer of The Multiplex Frontier

Rashmi ShivniandDrug Discovery News | | 10 min read

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An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Auricular vagal neuromodulation therapy is a non-invasive and non-surgical treatment that could aid cardiovascular disease management, Long COVID relief, and more.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

Improved technologies have allowed researchers to delve deeper into T cell biology, but the traditional naming scheme has struggled to keep up with new findings.

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Frogs that freeze themselves solid in the winter and thaw in the spring inspired methods to extend the storage time for transplantable organs.

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue

Research Resources

Podcasts

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

A streamlined, automated process helps scientists coordinate site-ready production-level whole genome sequencing results.

Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

In this webinar, learn how scientists are using cutting-edge spatial proteomics technologies to advance their understanding of cellular organization in healthy and diseased tissues.

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Scientists rely on cytokines, growth factors, and other agents to direct and create different types of organoid models.

Products

Product News

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by next-generation aminooxy chemistry.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

VANTAstar Flexible microplate reader with simplified workflows