A woman getting out of bed next to an alarm clock. People with advanced sleep phase trait have early sleep onset and offset due to genetic mutations leading to shorter circadian period.

| 4 min read

The Genetic Variants Behind "Early Bird" Sleep Patterns

Identifying the mutations that underly unusual sleep traits can provide insights into the biology of sleep and circadian function in humans.

Petros Giannikopoulos (right) and Fyodor Urnov (left) stand in the lab where the on-demand CRISPR therapy was produced. They are both wearing blue shirts and glasses.

| 5 min read

Baby KJ’s Bespoke Gene Therapy Is a Masterclass in Scientific Collaboration

Diagram showing epigenome editing using DNA methylation tools and recombinant proteins to control gene expression in human cells.

| 10+ min read

A New Era of Epigenetic Medicines

genetic disease

Hands wearing blue gloves use scissors and forceps to cut DNA.

David Liu Wins 2025 Breakthrough Prize for Base Editing and Prime Editing

Hannah Thomasy, PhD | | 9 min read

A close-up image of two fruit flies. These fruit flies are useful models in studying genetic variations.

From Flies to Families: How a Gene Variant May Shield Against Seizures

Laura Tran, PhD | | 3 min read

An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

Charles River Laboratories, Inc.andThe Scientist | | 3 min read

iStock

Catch Me If You Can: Sequencing Screens for Rare Disease Genes

The Scientist | | 1 min read

The heart sections on the left present defects while the hearts on the right do not show defects.

Genetic Signatures of a Defective Heart

Mariella Bodemeier Loayza Careaga, PhD | | 4 min read

Keeping Kidneys Healthy with a Hand from AI

Aparna Nathan, PhD | | 3 min read

MRI images of brains from patients with epilepsy

Defending against Dravet

Aparna Nathan, PhD | | 3 min read

Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University

The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease

Niki Spahich, PhD | | 3 min read

Researchers in George Church’s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.

A Pioneer of The Multiplex Frontier

Rashmi ShivniandDrug Discovery News | | 10 min read

Page 1 of 6 - 61 Total Items

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

A brown dog stares at a spoon of peanut butter in front of its face with wide eyes.

Why Do Dogs Love Peanut Butter?

The reason dogs beg, sit, stay, and shake for peanut butter could be both evolutionarily wired and learned behavior.

A cross section of a pine stem shows cells stained purple and blue.

The Biggest Breakthroughs in Cell Biology in 2025

From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

A close-up image of a fly landing on a dessert

What Happens When a Fly Lands on Your Food?

Flies carrying disease-causing microbes will likely contaminate the food they touch, but different factors determine whether the person who eats it will get sick.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

Individual NGS methods come with their own pros and cons, but automation optimization solutions exist for all NGS workflows.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Biotium's new TyraMax™ Amplification Dyes and Kits are available with the widest selection of colors for spatial analysis

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services