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A pregnant woman is talking to a doctor.
| 4 min read
A planned first-in-human trial aims to treat GM1 gangliosidosis in utero, possibly laying the foundation for prenatal gene therapies for other genetic diseases.

genetic disease

Petros Giannikopoulos (right) and Fyodor Urnov (left) stand in a lab where an on-demand therapy was made to treat Baby KJ. They are both wearing blue shirts and glasses.

Baby KJ’s Bespoke Gene Therapy Is a Masterclass in Scientific Collaboration

Diagram showing epigenome editing using DNA methylation tools and recombinant proteins to control gene expression in human cells.

A New Era of Epigenetic Medicines

Hands wearing blue gloves use scissors and forceps to cut DNA.

David Liu Wins 2025 Breakthrough Prize for Base Editing and Prime Editing

A close-up image of two fruit flies. These fruit flies are useful models in studying genetic variations.

From Flies to Families: How a Gene Variant May Shield Against Seizures

An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

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Catch Me If You Can: Sequencing Screens for Rare Disease Genes

The heart sections on the left present defects while the hearts on the right do not show defects. 

Genetic Signatures of a Defective Heart

Keeping Kidneys Healthy with a Hand from AI

MRI images of brains from patients with epilepsy

Defending against Dravet

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A person on an operation table getting anesthesia. A study revealed sex differences in ketamine anesthesia.

Female Brains Wake Up from Anesthesia Differently Than Male Brains

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A woman in her 60s wears a yellow tank top and brown-rimmed glasses while placing a hormone-replacement patch on her upper arm.

Flawed Studies Linked Menopausal Hormone Therapy to Breast Cancer

A hand holding $100 bills reaches out of a green-colored laptop screen, indicating a bribe.

Publisher Investigates an Alleged Peer Review Extortion Attempt

Multimedia

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
A model of a brain made of flat, multicolored pieces stacked together.

Mapping Tissues with Spatial Biology

August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

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Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi

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Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

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