A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
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DNA Methylation Influences Replication and Genome Organization
DNA Methylation Influences Replication and Genome Organization

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.

ABOVE: ISTOCK.COM, SELVANEGRA

genome architecture

A microscope image of a dinoflagellate.
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
Researchers Fuse Chromosomes to Create New Yeast Strains
Diana Kwon | Aug 1, 2018
Saccharomyces cerevisiae showed only minor alterations in growth and gene expression when its 16 chromosomes were combined.
DNA Loop-the-Loops
Kate Yandell | Dec 11, 2014
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Architecture Reveals Genome’s Secrets
Sabrina Richards | Nov 25, 2012
Three-dimensional genome maps are leading to a deeper understanding of how the genome’s form influences its function.