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Image of a woolly mammoth skin from the Siberian permafrost.
Rebuilding the Genome of Woolly Mammoths
A well-preserved 52,000-year-old woolly mammoth skin sample with fossils of ancient chromosomes could offer a glimpse into the history of life.
Rebuilding the Genome of Woolly Mammoths
Rebuilding the Genome of Woolly Mammoths

A well-preserved 52,000-year-old woolly mammoth skin sample with fossils of ancient chromosomes could offer a glimpse into the history of life.

A well-preserved 52,000-year-old woolly mammoth skin sample with fossils of ancient chromosomes could offer a glimpse into the history of life.

genome architecture

TSS
Genomes Across the Tree of Life
The Scientist | Mar 23, 2023 | 2 min read
Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.
The giant virus <em >Pandoravirus neocaledonia&nbsp;</em>inside the amoeba <em>Acanthamoeba castellanii</em>.
Giant Viruses Grew Out of Small Ones: Study
Kamal Nahas, PhD | Feb 13, 2023 | 4 min read
A study employing CRISPR/Cas9 to explore the evolutionary beginnings of some giant viruses finds evidence their large genomes arose from gene duplications.
A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
Abby Olena, PhD | Sep 22, 2021 | 3 min read
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
A microscope image of a dinoflagellate.
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021 | 5 min read
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
Researchers Fuse Chromosomes to Create New Yeast Strains
Diana Kwon | Aug 1, 2018 | 4 min read
Saccharomyces cerevisiae showed only minor alterations in growth and gene expression when its 16 chromosomes were combined.
DNA Loop-the-Loops
Kate Yandell | Dec 11, 2014 | 4 min read
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Architecture Reveals Genome’s Secrets
Sabrina Richards | Nov 25, 2012 | 4 min read
Three-dimensional genome maps are leading to a deeper understanding of how the genome’s form influences its function.
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