Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

histones
Lasker Awards Recognize Work on Histones, Anesthesia, RNA
Lasker Awards Recognize Work on Histones, Anesthesia, RNA
Shawna Williams | Sep 11, 2018
This year’s winners are C. David Allis, Michael Grunstein, John Glen, and Joan Steitz.
As Bees Specialize, So Does Their DNA Packaging
As Bees Specialize, So Does Their DNA Packaging
Shawna Williams | Sep 11, 2018
A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.
Epigenetic Mechanism Tunes Brain Cells
Epigenetic Mechanism Tunes Brain Cells
Amanda B. Keener | Jul 2, 2015
Regular replacement of histones in human and murine neurons is required for neuronal plasticity, a study shows.
Silencing Surprise
Silencing Surprise
Jenny Rood | Jun 1, 2015
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
Heritable Histones
Heritable Histones
Ruth Williams | Sep 18, 2014
Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.
Stockpiling Histones
Stockpiling Histones
Kerry Grens | Feb 1, 2013
Histones stored on lipid droplets in fly embryos provide a backup supply when newly synthesized ones are lacking.
Conserved Chromatin?
Conserved Chromatin?
Ed Yong | Dec 10, 2012
Archaea packages DNA around histones in a similar way to eukaryotes, suggesting that fitting a large genome into a small space was not the original role of chromatin.
A Reprogramming Histone
A Reprogramming Histone
Beth Marie Mole | Oct 29, 2012
The scientist who pioneered cloning has found that a histone may act as a cellular reset button.