ISTOCK, FROM2015
Methylation mystery
Methylation mystery
David Allis from Rockefeller University and colleagues used a biochemical pull-down assay and found that the protein WDR5, a common part of histone methyltransferase complexes, associates specifically with dimethylated H3K4 nucleosomes.
Methylation mystery
Methylation mystery

David Allis from Rockefeller University and colleagues used a biochemical pull-down assay and found that the protein WDR5, a common part of histone methyltransferase complexes, associates specifically with dimethylated H3K4 nucleosomes.

David Allis from Rockefeller University and colleagues used a biochemical pull-down assay and found that the protein WDR5, a common part of histone methyltransferase complexes, associates specifically with dimethylated H3K4 nucleosomes.

histones
Flu Fights Dirty
Hayley Dunning | Sep 1, 2012
Mimicking a host-cell histone protein offers flu a sneaky tactic to suppress immune response.
Boosting Antipsychotic Drugs
Ed Yong | Aug 5, 2012
Chemicals that change the way DNA is packaged could improve the effects of current antipsychotics.
DNA, Contortionist
Kerry Grens | Aug 1, 2012
The DNA forms known as G-quadruplexes are finally discovered in human cells.
Deep Tissue Treatment
Tia Ghose | Sep 1, 2011
A new, genetically encoded tag for electron microscopy may revolutionize studies of specific proteins in cells and tissues.
The Mark of Faith
Robert E. Kingston | Mar 1, 2011
Testing a central tenet of epigenetic regulation
Burning Chromatin at Both Ends
Burning Chromatin at Both Ends
Karen Hopkin | Mar 1, 2009
Shiv Grewal has seen both late nights and early mornings in the lab – and connections between seemingly disparate elements that other molecular biologists might miss.
Support for histone code?
Support for histone code?
Brendan Maher | May 22, 2006
Four papers released online today detail some of the work from David Allis's group and others on chromatin remodeling.