immune rejection

Scientists are banking various samples from recipients of donated uteruses to learn all they can about the biology of the organ, and about transplantation more generally.

With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.

Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.

In most vertebrates, the absence of adaptive immunity would be catastrophic, but in some deep-sea angler fish species, it enables their “wild” and “wacky” mating habits.

A proof-of-concept study uses a strategy similar to the way tumors evade immune detection. The new limbs survive for more than 200 days.

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.

Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.

Following face transplant, T cells from donor skin appear to be active at sites of rejection, perhaps to protect the tissue from attack by the recipient immune system.

Researchers uncover more evidence that reprogrammed stem cells are not attacked by the immune system, suggesting they may one day serve as effective therapies.

Reprogrammed stem cells are not attacked by the immune system, or are they?

Preliminary data from human embryonic stem cell trials for two degenerative eye disorders are promising, but challenges remain for more complex tissues.