Abstract geometric heart with plexus effect on blue background
Man Receives Transplanted Heart from Genetically Modified Pig
The procedure, performed last Friday, is a milestone in a long effort to boost the number of organs available for safe transplantation.
Man Receives Transplanted Heart from Genetically Modified Pig
Man Receives Transplanted Heart from Genetically Modified Pig

The procedure, performed last Friday, is a milestone in a long effort to boost the number of organs available for safe transplantation.

The procedure, performed last Friday, is a milestone in a long effort to boost the number of organs available for safe transplantation.

ABOVE: © ISTOCK.COM, HANNA SOVA
immune rejection
Pink-toned illustration of the uterus with a zoom of the inflamed cervix and of the uterine endometrium and immune cells found there
Infographic: Research Questions to Be Tackled by Uterus Transplants
Jef Akst | Aug 1, 2021
Scientists are banking various samples from recipients of donated uteruses to learn all they can about the biology of the organ, and about transplantation more generally.
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Asher Jones | Apr 1, 2021
Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.
deep-sea anglerfish Melanocetus johnsonii mating parasitic male immunology adaptive immune system cytotoxic t cell antibody
For Mates to Fuse Bodies, Some Anglerfish Have Lost Immune Genes
Katarina Zimmer | Jul 30, 2020
In most vertebrates, the absence of adaptive immunity would be catastrophic, but in some deep-sea angler fish species, it enables their “wild” and “wacky” mating habits.
Transplant Method Avoids Rejection of Donor Leg for Months in Rats
Abby Olena | Mar 13, 2020
A proof-of-concept study uses a strategy similar to the way tumors evade immune detection. The new limbs survive for more than 200 days.
Preterm Labor May Be Sparked by Fetal Immune Reaction
Ruth Williams | Apr 25, 2018
Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  
Toward Preventing Transplant Rejection with Immunologically Matched Stem Cells
Ruth Williams | Sep 15, 2016
Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.
Done with Immunosuppressants
Jef Akst | Jul 3, 2014
Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.
Facing Rejection
Kate Yandell | Jan 17, 2014
Following face transplant, T cells from donor skin appear to be active at sites of rejection, perhaps to protect the tissue from attack by the recipient immune system.
Stem Cells Not Rejected
Dan Cossins | Jan 25, 2013
Researchers uncover more evidence that reprogrammed stem cells are not attacked by the immune system, suggesting they may one day serve as effective therapies.
Debate Over Stem Cell Effectiveness
Ed Yong | Jan 9, 2013
Reprogrammed stem cells are not attacked by the immune system, or are they?
Eye Trials Give Hope for Stem Cells
Hannah Waters | Jan 24, 2012
Preliminary data from human embryonic stem cell trials for two degenerative eye disorders are promising, but challenges remain for more complex tissues.