A slice of rat brain showing various labelled proteins, such as the neurotransmitters dopamine (yellow) and acetylcholine (magenta).
| 3 min read
Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could label proteins in millions of cells.

immunohistochemistry

Discover How CF® Dyes Let Scientists Delve Deeper into Biological Phenomena

CF® Dyes: Clearer Fluorescent Results

Lipofuscin autofluorescence was quenched using EverBrite TrueBlack® Hardset Mounting Medium®, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.

Stepping Out of the Background

An abstract rendering of laboratory flasks with green and pink glowing liquid and scientific shapes floating above.

Traditional Techniques, New Applications

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Science Summarized: Putting Cells in Spatial Context

Technique Talk: Developing and Optimizing Immunohistochemistry Protocols

Technique Talk: Developing and Optimizing Immunohistochemistry Protocols

Efficient and Flexible Spatial Multiplexing: Assay Development Guidelines for ChipCytometryTM

Efficient and Flexible Spatial Multiplexing: Assay Development Guidelines for ChipCytometryTM

From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.

Broadening Tumor Molecular Profiling Horizons

Apply to bring spatial -omics research to the next level

Funding Opportunity: Stepping Up Spatial -Omics

spatial CRISPR screen for cancer

A Brave New World for Spatial Genomics in Cancer Research

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Muskoxen Headbutts May Cause Brain Damage: Study

chipcytometry-tissue

Revolutionizing Cellular Phenotyping with Multiplex Tissue Imaging

Discover how glycosylation affects health and disease

Exploring the World of Glycobiology

Visualize spatial gene and protein expression patterns in intact brain tissue

Molecular Mapping of the Brain Using Spatial Transcriptomics

Stem Cells in Human Teeth Follow the Rules of Their Environment

How Laboratory Testing Supports Clinical Trials

Technique Talk: The Basics of Immunohistochemistry

CAR T Cells Derived from Stem Cells Target HIV Tissue Reservoirs in Monkeys

Making IHC as Simple as ABC

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Large clumps of bacteria (pink) entrapped by webs of DNA (green) released by neutrophils in human urine.

When a Urinary Tract Infection Strikes, What Protects the Kidneys?

Illustration of a transparent, blue outlined synapse with red neurotransmitters passing between them. More out-of-focus blue neurons are in the background.

ALS Disturbs Sleep Prior to Symptom Onset

Mosquitoes on a red membrane against a white background.

Zika Hacks Host Skin Chemistry to Lure Mosquitoes

Multimedia

Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

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Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

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Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

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Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

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An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

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Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

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Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

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Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

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Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

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Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer