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Artist’s rendition of the molecular structure of a ribosome (blue and purple) as it produces a polypeptide chain (red) from an mRNA template (orange and gray), with tRNA molecules (dark purple) shuttling amino acids.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

infertility
Ctrl+C and Ctrl+V computer keyboard button with cable isolated on white background
Opinion: The Reproductive Technology Advances No One Asked For
John D. Loike and Alan Kadish | Jun 22, 2022 | 4 min read
Cloning and parthenogenesis of humans wouldn’t align with bioethical principles.
A white mouse huddles with some of her nine-day-old pups.
In Vivo Gene Therapy Cures Infertility in Mice
Dan Robitzski | May 2, 2022 | 2 min read
Mice rendered infertile through ovary cell–targeting mutations gave birth to seemingly normal offspring through natural mating after a virus-based gene therapy was injected into their ovaries.
Pink rat pups piled on top of each other.
Rat Sperm Generated from Stem Cells
Alejandra Manjarrez, PhD | Apr 7, 2022 | 4 min read
Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.
Opinion: Treating Infertility as a Disease
Kate O'Neill | Aug 1, 2021 | 4 min read
For too long, a physiological inability to conceive or carry a child through to birth has been seen as a minor medical issue.
A New View of My Own Past
Jef Akst | Aug 1, 2021 | 6 min read
Hearing others’ perspectives on infertility and pregnancy has me reconsidering my own reproductive journey.
Women’s Cervical Mucus Prefers Some Sperm Over Others 
Abby Olena, PhD | Aug 18, 2020 | 3 min read
In human male-female pairs with a less similar suite of genes for human leukocyte antigens, sperm fare better when exposed to cervical mucus.
Single-Cell Analysis of Ovarian Cortex Fails to Find Stem Cells
Amy Schleunes | Mar 6, 2020 | 5 min read
The controversial oogonial stem cells eluded a team of Swedish researchers who mapped high-quality tissue samples of the human ovary, prompting more questions about the cells’ existence.  
Baby Born from Egg that Was Matured and Frozen in the Lab
Catherine Offord | Feb 19, 2020 | 2 min read
A cancer patient who underwent the new fertility preservation procedure successfully gave birth five years after her immature eggs were collected.
Image of the Day: Old Ovaries
Amy Schleunes | Feb 6, 2020 | 1 min read
Oxidative stress associated with aging damages ovarian cells in both humans and nonhuman primates.
Human Testicles Contain Endocannabinoid System Components
Ruth Williams | Sep 19, 2019 | 3 min read
Proteins that synthesize, bind, and degrade endocannabinoids are present in the body’s sperm factories, suggesting that the use of cannabis may directly affect them.
crispr baby he jiankui gene editing genome fertility clinic emails
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019 | 1 min read
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.
a baby's feet
“Three-Parent” IVF Trialed for Infertility
Shawna Williams | Jan 25, 2019 | 2 min read
A company announces the first pregnancy in a study of whether donor mitochondria can boost IVF’s odds of success.
Opinion: Three-Parent Embryos—A Slippery Slope?
John D. Loike and Alan Kadish | Jun 14, 2018 | 4 min read
The use of pronuclear transfer to treat infertility must first be backed by evidence it can work in cases where parents seek to avoid mitochondrial mutations.
Image of the Day: Sperm Protectors
The Scientist Staff | Aug 18, 2017 | 1 min read
Among their many functions, macrophages in mouse testes guard sperm against attacks by other immune cells. 
Image of the Day: Embryoid
The Scientist Staff | Aug 11, 2017 | 1 min read
Using human pluripotent stem cells, scientists engineered an amniotic sac-like structure, potentially useful for uncovering the elusive cellular signals that lead to infertility.
Smartphone Semen Assay
Kerry Grens | Mar 23, 2017 | 1 min read
An app-based sperm analyzer screens for signs of male infertility.
Study: IVF Media Affects Treatment Outcomes
Ben Andrew Henry | Aug 24, 2016 | 1 min read
Differences between cultures used for in vitro fertilization techniques can impact fertility and offspring health, researchers report.
Skin Cells Turned Into Immature Sperm
Tanya Lewis | Apr 29, 2016 | 1 min read
The reprogrammed germ-like cells were unable to fertilize eggs, however. 
A Benefit of Failed Pregnancy?
Ruth Williams | Apr 9, 2015 | 3 min read
Scientists find a common genetic variant in mothers that decreases the chance of successful pregnancy.
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