innate immune system

Males recovered from mild COVID-19 have baseline immune states primed to mount stronger responses to future challenges.

The “tripledemic” shines a spotlight on viral interference, in which one infection can block another.

Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 

In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.

Deletions in the sleepy lizard genome leave it without an important type of T cells found in most other vertebrates.

A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.

In mice, a kind of immune memory appears to protect the cells against future harm, a finding that could provide insight into treatments for irritable bowel syndrome and other inflammatory digestive conditions.

Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response.

The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.

A comparison of interferon-related genes across 20 primate genomes reveals differences in the speed at which they evolve and new targets for antiviral discovery efforts.

In a new study, human and mouse cells recognized only one in five bacterial species collected from more than a mile below the Pacific Ocean’s surface.

A recent study sheds light on a previously unknown mechanism for fending off the pathogen, and potentially other viruses as well.

A pathway involved in the adaptive immune system, a relative newcomer in the world of pathogen defense, may have a more ancient role in protecting cells from invading viruses.

Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.