Special Report
Seeking an Early COVID-19 Drug, Researchers Look to Interferons
Seeking an Early COVID-19 Drug, Researchers Look to Interferons
These antiviral proteins are produced by the body as a natural defense against viral infections and synthetic interferons might help prevent or treat the beginning stages of SARS-CoV-2 infection.
Seeking an Early COVID-19 Drug, Researchers Look to Interferons
Seeking an Early COVID-19 Drug, Researchers Look to Interferons

These antiviral proteins are produced by the body as a natural defense against viral infections and synthetic interferons might help prevent or treat the beginning stages of SARS-CoV-2 infection.

These antiviral proteins are produced by the body as a natural defense against viral infections and synthetic interferons might help prevent or treat the beginning stages of SARS-CoV-2 infection.

innate immunity
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
Abby Olena | May 21, 2020
The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Catherine Offord | Jan 24, 2020
This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.
Innate Immune Cells May Actually Remember Their Targets
Innate Immune Cells May Actually Remember Their Targets
Emma Yasinski | May 10, 2019
Human natural killer cells, previously considered not to participate in adaptive immunity, remember viral antigens after initial exposures, according to a new study.
Image of the Day: An Infectious Glow
Image of the Day: An Infectious Glow
Carolyn Wilke | Mar 7, 2019
In CRISPRed fruit flies that lack certain antimicrobial peptides, bacterial infections flourish, as revealed by fluorescent markers.
Some Antibiotics Rev Up Host Immune Response to Viruses
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
Natural Selection Kept Neanderthal DNA in Modern Humans
Natural Selection Kept Neanderthal DNA in Modern Humans
Anna Azvolinsky | Dec 29, 2016
Interbreeding with Neanderthals appears to have reintroduced genetic sequences related to innate immunity that had been lost as humans migrated out of Africa. 
One Way Placenta Deflects Zika Infection
One Way Placenta Deflects Zika Infection
Kerry Grens | Apr 5, 2016
Certain immune cells surrounding the organ appear to block viral entry.
Mother’s Microbiome Shapes Offspring’s Immunity
Mother’s Microbiome Shapes Offspring’s Immunity
Anna Azvolinsky | Mar 17, 2016
The maternal gut microbiome guides neo- and postnatal immune system development, a mouse study shows. 
Viral Remnants Help Regulate Human Immunity
Viral Remnants Help Regulate Human Immunity
Jyoti Madhusoodanan | Mar 3, 2016
Endogenous retroviruses in the human genome can regulate genes involved in innate immune responses.