interferon

A comparison of interferon-related genes across 20 primate genomes reveals differences in the speed at which they evolve and new targets for antiviral discovery efforts.

Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.

Researchers detail how viral proteins interact with host RNA to disrupt the cell’s ability to fight back against infection.

These antiviral proteins are produced by the body as a natural defense against viral infections and synthetic interferons might help prevent or treat the beginning stages of SARS-CoV-2 infection.

The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.

The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

Julius Youngner collaborated with Jonas Salk on the polio vaccine, and later identified interferon gamma and contributed to an equine influenza vaccine.

Type I interferon organizes several immune mechanisms to suppress B cell responses to a chronic viral infection.

Certain immune cells surrounding the organ appear to block viral entry.

A better knowledge of the pathogenesis of emerging zoonotic diseases is crucial if we want to prepare for “the next Ebola.”

Jean Lindemann, the virologist who helped figure out that interferons were responsible for anti-viral responses, has passed away at age 90.

Neurons may use interferon signals transmitted over great distances to fend off viral infection.

Professor, Microbiology, Icahn School of Medicine at Mount Sinai. Age: 36

January 2014 Scientist to Watch Benjamin tenOever discusses his research.

Commercial kits use fluorescent beads to probe dozens of cytokines in one reaction.

An interferon found in the female reproductive tract may help guard against sexually transmitted diseases such as herpes.