Blue, green, and red dots make a worm-like shape against a black background, signifying human organoids grafted in mice that secreted insulin.
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Transplanting human gastric organoids engineered to release insulin in diabetic mice reduced hyperglycemia, offering a therapeutic avenue for type 1 diabetes.

intestinal organoids

Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

Modeling the Intestines with Mini Guts

Modeling the Intestines with Mini Guts

Discover the foundations and future of organoid research technologies.

Levitating Organoid Cultures to Reach                                   Higher Research Heights

A microscopy image of intestinal crypts in human tissue.

Trust Your Gut: Screening Drugs Using Novel Intestinal Models

Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid

Internal Clock Disruptions Increase Colon Cancer Risk in Mice

in love with the shape of you

In Love with the Shape of You: Physical Scaffolding Defines Organoid Patterning

Image of the Day: Goo for Growing Organoids

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A cross section of a pine stem shows cells stained purple and blue.

The Biggest Breakthroughs in Cell Biology in 2025

Gollum, the extremely territorial character from The Lord of the Rings, famous for his line, “My precious,” sits on a rock, looking up.

The Gollum Effect: 44 Percent of Scientists Report Territorial Research Experiences

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

person doing the finger prick test for measuring blood glucose. A new noninvasive method could provide an alternative to such invasive blood tests.

Measuring Blood Sugar Without Painful Pricks? A New Test Scans Skin

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

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December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

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Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

Fujifilm
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

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