Image of the Day: Goo for Growing Organoids

Scientists engineered a synthetic, nutrient-rich gel that feeds growing organoids as they mature from human pluripotent stem cells into 3-D bowels.


Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

A mature intestinal organoid, grown from human pluripotent stem cells and a synthetic growth-promoting hydrogelMIGUEL QUIRÓS, UNIVERSITY OF MICHIGANTo cultivate organoids in culture, scientists bathe them in growth-promoting materials derived from mice. But this limits their use in treating human diseases due to the risk for zoonotic infections. To solve this problem, researchers engineered a synthetic gel that can also do the job.

See R. Cruz-Acuña et al., “Synthetic hydrogels for human intestinal organoid generation and colonic wound repair,” Nature Cell Biology, doi:10.1038/ncb3632, 2017.

Correction (October 27): The original credit for the image incorrectly listed a different coauthor. The Scientist regrets the error.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo