Slime mold colony with volcano-like spores
Cancer-like Slime Mold Growth Hints at Multicellularity’s Origins
The poorly understood Fonticula alba, a relative of fungi and animals, hunts bacteria with a mechanism that resembles cancer and fungal growth.
ABOVE: Marko Kaksonen
Cancer-like Slime Mold Growth Hints at Multicellularity’s Origins
Cancer-like Slime Mold Growth Hints at Multicellularity’s Origins

The poorly understood Fonticula alba, a relative of fungi and animals, hunts bacteria with a mechanism that resembles cancer and fungal growth.

The poorly understood Fonticula alba, a relative of fungi and animals, hunts bacteria with a mechanism that resembles cancer and fungal growth.

ABOVE: Marko Kaksonen

cell culture

Photo of lab-grown chicken from Eat Just, Inc.
Cultured Meat Advances Toward the Market
Abby Olena | Feb 14, 2022
The biotech industry is chipping away at the obstacles standing between the lab and the dinner plate.
Lizard on glass tank
Engineered Stem Cells Grant Geckos “Perfectly” Regenerated Tails
Chloe Tenn | Nov 5, 2021
Geckos injected with neural stem cells modified to block cartilage growth developed the skeletal and nervous components normally lacking from regrown tails.
Meat sample in open disposable plastic cell culture dish in modern laboratory or production facility.
Removing the Animals from Lab-Grown Meat
Niki Spahich, PhD | May 9, 2022
Growing meat in a laboratory may seem like science fiction, but researchers around the world are perfecting the culture of animal muscle intended for human consumption.
An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena | Oct 29, 2021
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
corals in water with fish
First Immortal Cell Line Cultured for Reef-Building Corals
Amanda Heidt | Jul 1, 2021
Lab-grown cells from the reef-building coral Acropora tenuis provide new opportunities to study bleaching, symbioses, and biomineralization.
Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic.
The Scientist Speaks - Preventing the Next Pandemic with Organ Chips
Nele Haelterman, PhD | Mar 30, 2022
Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic.
Infographic: How Scientists Are Creating Coral Cell Lines
Amanda Heidt | Jul 1, 2021
Stable, long-term cell lines will enable scientists to study everything from coral bleaching to biomineralization, knowledge that may help protect corals from ongoing climate change.
heath hen Tympanuchus cupido de-extinction grouse pgc germline transmission cultured germ cell transmission
The Booming Call of De-extinction
W. S. Roberts | Oct 19, 2020
Scientists seek to combine genome editing with a technique used in chicken breeding to try to bring back lost birds.
The advantages of 3-D cell culture
The Advantages of 3-D Cell Culture
MilliporeSigma | Mar 29, 2022
3-D cell culture narrows the gap between in vitro and in vivo.
Stomach Acid & Heartburn Drugs Linked with COVID-19 Outcomes
Ashley Yeager | Oct 7, 2020
While sick with COVID-19, President Trump is taking an antacid. Doctors have been exploring whether these medicines can treat SARS-CoV-2 infections, and the results are mixed.
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
Abby Olena | May 21, 2020
The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.
Are your cell lines what you think they are?
Are Your Cell Lines What You Think They Are?
MilliporeSigma | Mar 29, 2022
Learn how to identify contamination and authenticate your cell lines.
Cells’ Response to SARS-CoV-2 Different from Flu, RSV
Abby Olena | Mar 31, 2020
The host transcriptional signature elicited by the coronavirus appears to be less robust and lacks the induction of key antiviral genes.
hipscs human induced pluripotent stem cell culture medium e8 b8 fibroblast growth factor fgf2
New iPSC Culture Medium Promises Weekends Off at Low Costs
Katarina Zimmer | Jan 20, 2020
Biologists have published a DIY recipe for human induced pluripotent stem cell maintenance, which they estimate costs 3 percent of commercial media prices.
Why might cells die or fail to thrive in culture?
Why Might Cells Die or Fail to Thrive in Culture?
MilliporeSigma | Mar 29, 2022
Learn more about cell culture best practices.
a photo of ampules stored in wire racks
Scripps Acquires Pfizer’s Massive Microbial Library
Jef Akst | Jan 9, 2020
The East Coast campus of the research institute received shipments of freeze-dried or frozen samples of more than 210,000 microbial strains, which scientists plan to mine for potentially useful natural products.
Potential Causes of Irreproducibility Revealed
Abby Olena | Jul 11, 2019
Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.
Salmonella living within macrophages can survive antibiotic treatment and potentially give rise to resistance by two different mechanisms that slow or arrest their growth.
Bacteria Go Dormant to Survive Antibiotics and Restart Infections
Niki Spahich, PhD | Mar 7, 2022
In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.
Wellcome sanger institute genome campus closing animal mouse facility laboratory
Wellcome Sanger Institute to Close Animal Facility
Chia-Yi Hou | Jun 10, 2019
The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.