Potential Causes of Irreproducibility Revealed
Potential Causes of Irreproducibility Revealed
Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.
Potential Causes of Irreproducibility Revealed
Potential Causes of Irreproducibility Revealed

Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.

Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.

cell culture
Wellcome Sanger Institute to Close Animal Facility
Wellcome Sanger Institute to Close Animal Facility
Chia-Yi Hou | Jun 10, 2019
The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.
Image of the Day: Shrink Ray
Image of the Day: Shrink Ray
Jef Akst | Oct 30, 2018
A near-infrared laser warps a tissue culture surface to mimic natural cellular environments.
Speeding Up Stem Cell Growth
Speeding Up Stem Cell Growth
Amber Dance | Sep 1, 2018
Scientists fiddle with formulas to boost the growth of their stem cell cultures.
Artificial Mouse Embryo Made in a Laboratory
Artificial Mouse Embryo Made in a Laboratory
Sukanya Charuchandra | Jul 25, 2018
The embryo, grown in a dish from several types of stem cells, went through gastrulation, a significant stage in development.
Archaea Family Tree Blossoms, Thanks to Genomics
Archaea Family Tree Blossoms, Thanks to Genomics
Amber Dance | Jun 1, 2018
Identification of new archaea species elucidates the domain’s unique  biology and sheds light on its relationship to eukaryotes.
Image of the Day: Goo for Growing Organoids
Image of the Day: Goo for Growing Organoids
The Scientist Staff, The Scientist Staff | Oct 24, 2017
Scientists engineered a synthetic, nutrient-rich gel that feeds growing organoids as they mature from human pluripotent stem cells into 3-D bowels.
Papers Based on Misidentified Cell Lines Top 32,000
Papers Based on Misidentified Cell Lines Top 32,000
Kerry Grens | Oct 16, 2017
An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.
Ready, Set, Grow
Ready, Set, Grow
Amber Dance | Sep 1, 2017
How to culture stem cells without depending on mouse feeder cells
Image of the Day: Plant Platforms
Image of the Day: Plant Platforms
The Scientist Staff | Mar 20, 2017
Stripping away everything except the cell walls from certain plants, scientists can create scaffolds for human cell cultures.