SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro
SARS-CoV-2 Protein Hampers Innate Immune Reaction In Vitro

The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.

The viral protein known as ORF3b limits the induction of the type I interferon response, which typically alerts other immune system components to the presence of a virus, in cultured cells.

cell culture
Cells’ Response to SARS-CoV-2 Different from Flu, RSV
Cells’ Response to SARS-CoV-2 Different from Flu, RSV
Abby Olena | Mar 31, 2020
The host transcriptional signature elicited by the coronavirus appears to be less robust and lacks the induction of key antiviral genes.
New iPSC Culture Medium Promises Weekends Off at Low Costs
New iPSC Culture Medium Promises Weekends Off at Low Costs
Katarina Zimmer | Jan 20, 2020
Biologists have published a DIY recipe for human induced pluripotent stem cell maintenance, which they estimate costs 3 percent of commercial media prices.
Scripps Acquires Pfizer’s Massive Microbial Library
Scripps Acquires Pfizer’s Massive Microbial Library
Jef Akst | Jan 9, 2020
The East Coast campus of the research institute received shipments of freeze-dried or frozen samples of more than 210,000 microbial strains, which scientists plan to mine for potentially useful natural products.
Potential Causes of Irreproducibility Revealed
Potential Causes of Irreproducibility Revealed
Abby Olena | Jul 11, 2019
Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.
Wellcome Sanger Institute to Close Animal Facility
Wellcome Sanger Institute to Close Animal Facility
Chia-Yi Hou | Jun 10, 2019
The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.
Image of the Day: Shrink Ray
Image of the Day: Shrink Ray
Jef Akst | Oct 30, 2018
A near-infrared laser warps a tissue culture surface to mimic natural cellular environments.
Speeding Up Stem Cell Growth
Speeding Up Stem Cell Growth
Amber Dance | Aug 31, 2018
Scientists fiddle with formulas to boost the growth of their stem cell cultures.
Artificial Mouse Embryo Made in a Laboratory
Artificial Mouse Embryo Made in a Laboratory
Sukanya Charuchandra | Jul 25, 2018
The embryo, grown in a dish from several types of stem cells, went through gastrulation, a significant stage in development.
Archaea Family Tree Blossoms, Thanks to Genomics
Archaea Family Tree Blossoms, Thanks to Genomics
Amber Dance | May 31, 2018
Identification of new archaea species elucidates the domain’s unique  biology and sheds light on its relationship to eukaryotes.