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Immunofluorescence light microscopy image of cancer cells growing in 2D with nuclei in blue, cytoplasm in red, and DNA damage foci in green.
Shining a Light on New Microscopy Technologies
From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.
Shining a Light on New Microscopy Technologies
Shining a Light on New Microscopy Technologies

From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.

From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.

Light microscopy

A photo of a dish in which cells, which look like small dots, have been enlarged and stained to make them visible to the naked eye.
New Swelling Technique Makes Cells Visible to the Naked Eye
Kamal Nahas, PhD | Jan 19, 2023 | 4 min read
A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.
A blue coelacanth with white speckles in the ocean
African Coelacanths May Live to Be 100: Study
Catherine Offord | Jun 18, 2021 | 2 min read
This evolutionarily ancient fish species has a lifespan that’s around five times longer than previously thought, and a gestation time of more than five years.
traced mouse neurons
Image of the Day: Brain Map
Nicoletta Lanese | Sep 6, 2019 | 1 min read
Scientists traced 1,000 neurons through the mouse brain, uncovering new details about how the organ is wired.
SLAP microscope
Image of the Day: Super Speedy Microscopy
Nicoletta Lanese | Aug 9, 2019 | 1 min read
Two-photon imaging captures chemical signaling between live mouse neurons on a millisecond timescale.
Image of the Day: Under the Microscope
Carolyn Wilke | Mar 5, 2019 | 1 min read
A virtual exhibition of C.R. Percival’s slides reveals the natural world up close.
Image of the Day: X-Ray Vision
Sukanya Charuchandra | Jun 28, 2018 | 1 min read
Using a unique microscope, researchers looked inside a yet-to-be identified pseudoscorpion from Peru.
Image of the Day: Feather Mites
The Scientist and The Scientist Staff | Feb 19, 2018 | 1 min read
Researchers used scanning electron microscopy to peer at bugs on several hummingbird species.
Seeing Double
Nicholette Zeliadt | Nov 1, 2013 | 7 min read
Combining two imaging techniques integrates molecular specificity with nanometer-scale resolution.
 
Mental Clarity
Kelly Rae Chi | Oct 31, 2013 | 1 min read
Karl Deisseroth and his team at Stanford University make mouse brains transparent to explore their inner workings.
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