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A green and white fish swimming underwater
Rockfish Genes Hold Clues to Human Longevity
By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.
Rockfish Genes Hold Clues to Human Longevity
Rockfish Genes Hold Clues to Human Longevity

By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.

By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.

longevity
White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Natalia Mesa, PhD | Sep 29, 2022 | 3 min read
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
Photo of a clock on a plate with cutlery on either side.
Opinion: Changing When and How Much We Eat May Extend Healthspan
Joseph S. Takahashi and Carla B. Green | Aug 1, 2022 | 4 min read
Fasting, eating only at certain times of day, and restricting overall calorie intake can collectively contribute to lifespan extensions in animals. Could the same hold true in humans?
Illustration of blue shiny mitochondria
Worms Live Longer with Mitochondria Powered by Light: Preprint
Alejandra Manjarrez, PhD | May 24, 2022 | 4 min read
Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021 | 3 min read
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
Fruit flies in a vial
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021 | 3 min read
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
Ginkgo’s Extreme Longevity Credited to Immune System
Lisa Winter | Jan 15, 2020 | 2 min read
Genes related to the immune system stay active throughout the tree’s life.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019 | 3 min read
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
longevity prediction estimate lifespan methylation telomere biomarkers eldely old age centenarian
Opinion: Biomarkers of Longevity Not Ready for the Clinic
John D. Loike and Ruth L. Fischbach | Sep 27, 2019 | 4 min read
The science isn’t there yet, nor are the known interventions that ought to be combined with delivering such predictions.
c elegans reproduction longevity gene TCER-1 health immune system genetics research model
C. elegans Healthier Without Longevity Gene
Chia-Yi Hou | Jul 17, 2019 | 2 min read
Worms with the reproduction-related TCER-1 gene deleted could fight off infection for longer and survived better when exposed to heat and radiation.
ccr5 delta32 genetic mutation hiv t cell
Genetic Mutation that Prevents HIV Infection Tied to Earlier Death
Emma Yasinski | Jun 3, 2019 | 3 min read
Those with two copies of the Δ32 allele in the CCR5 gene are 21 percent more likely to die by age 76, although it’s not clear why.
march 2019 the scientist profile
Master Decoder: A Profile of Kári Stefánsson
Anna Azvolinsky | Mar 1, 2019 | 9 min read
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
New Study Questions Whether Death Rate Levels Off in Old Age
Ashley P. Taylor | Dec 21, 2018 | 7 min read
A demographer’s model suggests the “mortality plateau” in the extreme elderly could be explained by clerical errors. Not everyone agrees.
Risk of Dying Levels Off in Super Old Age: Study
Kerry Grens | Jun 28, 2018 | 2 min read
The researchers say that their results are evidence we haven’t yet reached a limit to human lifespan.
Another Bird Telomere Study, Different Results
Anna Azvolinsky | Mar 21, 2018 | 2 min read
Two studies examining the effects of parents’ ages on their offsprings’ telomere lengths come to opposite conclusions.  
13-Million-Person Family Tree Reveals Stories of Human History
Ashley Yeager | Mar 1, 2018 | 2 min read
Crowdsourced data from Geni.com, which includes the actor Kevin Bacon, answers questions about marriage, migration, and more.
Could Rapamycin Help Humans Live Longer?
Anne N. Connor | Mar 1, 2018 | 4 min read
From extending lifespan to bolstering the immune system, the drug’s effects are only just beginning to be understood.
Study: Telomeres Don’t Shorten with Age in Longest-Lived Bats
Diana Kwon | Feb 7, 2018 | 1 min read
Researchers find that while bats in the Myotis genus don’t produce telomerase, the enzyme that lengthens telomeres, they possess 21 telomere maintenance–related genes.
Genetic Mutation in Amish Linked to Longer Life
Katarina Zimmer | Nov 16, 2017 | 1 min read
Mutations in both copies of SERPINE1 can result in blood clotting disorders, but carriers might enjoy longer lifespan and health benefits. 
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017 | 2 min read
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
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