New TALEN-based tools enable the organelle’s genome to be targeted and modified.

Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.

From regulating each other’s gene expression to encoding different parts of the same proteins, the two genome types in every eukaryotic cell are far from independent.

Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.

Mitochondrial DNA and other factors place our ancestors in southern Africa 200,000 years ago.

The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.

Researchers identify unique cases in which people inherited mitochondrial DNA not just from their mother but also from their father.

Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.

In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.