Bryan Sykes, Ancestral Genetics Expert, Dies at 73
Bryan Sykes, Ancestral Genetics Expert, Dies at 73
Sykes sequenced famous ancient remains, such as Ötzi and Cheddar Man, and was one of the first researchers to use mitochondrial DNA to trace genetic lineages.
Bryan Sykes, Ancestral Genetics Expert, Dies at 73
Bryan Sykes, Ancestral Genetics Expert, Dies at 73

Sykes sequenced famous ancient remains, such as Ötzi and Cheddar Man, and was one of the first researchers to use mitochondrial DNA to trace genetic lineages.

Sykes sequenced famous ancient remains, such as Ötzi and Cheddar Man, and was one of the first researchers to use mitochondrial DNA to trace genetic lineages.

mitochondrial DNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
Amanda Heidt | Jul 9, 2020
An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.
Infographic: A Gene Editor for Plant Mitochondrial DNA
Infographic: A Gene Editor for Plant Mitochondrial DNA
Ruth Williams | Mar 1, 2020
New TALEN-based tools enable the organelle’s genome to be targeted and modified.
Gene Editing Reaches Plant Mitochondria
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
Infographic: How the Mitochondrial and Nuclear Genomes Interact
Infographic: How the Mitochondrial and Nuclear Genomes Interact
Viviane Callier | Nov 1, 2019
From regulating each other’s gene expression to encoding different parts of the same proteins, the two genome types in every eukaryotic cell are far from independent.
The Two Genomes in Every Eukaryotic Cell
The Two Genomes in Every Eukaryotic Cell
Viviane Callier | Nov 1, 2019
Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.
The First Modern Humans Came from What Is Now Botswana: Study
The First Modern Humans Came from What Is Now Botswana: Study
Kerry Grens | Oct 28, 2019
Mitochondrial DNA and other factors place our ancestors in southern Africa 200,000 years ago.
Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting
Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting
John D. Loike | Dec 12, 2018
The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.
Fathers Can Pass Mitochondrial DNA to Children
Fathers Can Pass Mitochondrial DNA to Children
Anna Azvolinsky | Dec 4, 2018
Researchers identify unique cases in which people inherited mitochondrial DNA not just from their mother but also from their father.
Gene Editing Treats Mitochondrial Disorders in Mice
Gene Editing Treats Mitochondrial Disorders in Mice
Catherine Offord | Sep 25, 2018
Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.
Circulating Mitochondrial DNA Alerts Immune System to Danger
Circulating Mitochondrial DNA Alerts Immune System to Danger
Katarina Zimmer | Mar 1, 2018
In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.
Enzyme Required for Mitochondrial Genome Destruction
Enzyme Required for Mitochondrial Genome Destruction
Abby Olena | Mar 22, 2017
Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.
This Parasitic Plant Steals More Than Nutrients From Its Hosts
This Parasitic Plant Steals More Than Nutrients From Its Hosts
David Smith | Feb 1, 2017
The plant Lophophytum pilfers mitochondrial genes from the species it parasitizes.
Opinion: Ethical Considerations of “Three-Parent” Babies
Opinion: Ethical Considerations of “Three-Parent” Babies
John D. Loike and Nancy Reame | Dec 22, 2016
Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.
Clyde A. Hutchison III: Genome Sequencer and Synthetic Biologist
Clyde A. Hutchison III: Genome Sequencer and Synthetic Biologist
Anna Azvolinsky | Aug 1, 2016
From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome