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A karyotype of chromosomes mostly stained blue with one stained red and green
Researchers Fuse Mouse Chromosomes in Scientific First
The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.
Researchers Fuse Mouse Chromosomes in Scientific First
Researchers Fuse Mouse Chromosomes in Scientific First

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

mouse embryonic stem cells
microscope image series showing synthetic embryo development
Mouse Embryo: No Sperm, Egg, or Uterus Required
Christie Wilcox, PhD | Aug 2, 2022 | 3 min read
Using stem cells and a bioreactor, researchers generated living embryos that survived for more than a week and began to develop internal organs.
Eight Proteins Turn Mouse Stem Cells into Egglike Cells
Ashley Yeager | Dec 16, 2020 | 3 min read
The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  
Early Embryo Models Generated from Mouse Stem Cells
Abby Olena, PhD | Oct 17, 2019 | 4 min read
Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.
First Mouse Embryos Made from Two Fathers
Abby Olena, PhD | Oct 11, 2018 | 3 min read
The bipaternal pups died soon after birth, but mice with two mothers grew into fertile adults.
Artificial Mouse Embryo Made in a Laboratory
Sukanya Charuchandra | Jul 25, 2018 | 1 min read
The embryo, grown in a dish from several types of stem cells, went through gastrulation, a significant stage in development.
Meet the First Artificial Embryo Made From Stem Cells
Bob Grant | Mar 2, 2017 | 2 min read
Researchers report growing a mouse embryo using two types of early stem cells.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016 | 2 min read
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
From Stem Cell to Oocyte In a Dish
Anna Azvolinsky | Oct 17, 2016 | 4 min read
For the first time, scientists generate functional mouse eggs from stem cells in culture.
Mice Develop with Human Stem Cells
Karen Zusi | Dec 21, 2015 | 2 min read
Human embryonic stem cells and induced pluripotent stem cells participated normally in early mouse embryo development in a recent study.
Passenger Mutations Can Skew Results
Kate Yandell | Jul 7, 2015 | 4 min read
Some genetically engineered mice harbor unwanted mutations that hitchhike alongside desired modifications, affecting experimental outcomes.
New Stem Cell Identified
Anna Azvolinsky | May 6, 2015 | 4 min read
Researchers isolate an easy-to-manipulate, stable, and spatially distinct pluripotent cell type.  
New Stem Cell State
Anna Azvolinsky | Dec 10, 2014 | 3 min read
Through cellular reprogramming, researchers have produced a novel pluripotent mouse stem cell in vitro.
Week in Review: June 2–6
Tracy Vence | Jun 5, 2014 | 4 min read
The malnourished microbiome; innate immunity and beige fat; tools for stem cell self-renewal; predicting tomorrow’s PIs; MERS update
Minimal Toolkit for Stem Cell Self-Renewal
Anna Azvolinsky | Jun 5, 2014 | 3 min read
Researchers identify a network of a dozen transcription factors needed to maintain the pluripotent state of mouse embryonic stem cells. 
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