Surveillance Gaps: How Cancer Arises

Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.

The lab animals had more natural microbiomes seeded by wild mice, unlike conventional models that are kept in sterile conditions.

Machine learning could be the key to reducing the use of animals in experiments.

By zooming in on a developing mouse heart, scientists are studying whether defects in vasculature contribute to a thin muscle wall.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

Genetic mutations create lab mice with unusually long and short tails.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

The university is carrying out a review of animal handling in the now-closed lab of neuropsychologist Vedran Lovic.

Researchers have been using ultrasound to control brain activity, but studies in mice and guinea pigs show it also stimulates the auditory system, presenting a confounder for direct neural stimulation.

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

The treatment also curbed the growth of nearby metastases that did not receive the drug.

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.

Lab-grown muscle stem cells from mice mimic the formation of muscle fibers in vivo. 

The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

The mini-organs reproduce the two cell layers present in mouse skin and the development of hair follicles, providing a potential model for skin and hair research.

Researchers uncover the central role of a protein linked to Fragile X Syndrome in mice, one of the leading causes of autism and intellectual disability.

Researchers have succeeded in mapping the complex paths of 300 neurons in the mouse brain.