A mouse brain showing activated neurons (white) in the brainstem 3 hours after LPS injection.
Research Pinpoints the Neurons Behind Feeling Sick
Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.
Research Pinpoints the Neurons Behind Feeling Sick
Research Pinpoints the Neurons Behind Feeling Sick

Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.

Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds.

mouse models
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez | Sep 15, 2022
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
LAKSAMEE CAVE
Clinton Cave Investigates How Brain Cells Communicate
Andy Carstens | Sep 1, 2022
The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.
Neurons traversing the brain with an area of red neurodegeneration
LabTalk Podcast - The New Era of Neurodegeneration Research
The Scientist Creative Services Team
Erdem Gültekin Tamgüney discusses the future of neurodegeneration research and his work exploring the link between stroke and Parkinson’s disease.
Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid
Internal Clock Disruptions Increase Colon Cancer Risk in Mice
Shafaq Zia | Aug 19, 2022
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
Scientific illustration of a migrating breast cancer cell.
Breast Cancer Cells Churn Out Cholesterol to Fuel Metastasis
Alejandra Manjarrez | Feb 4, 2022
A study uncovers a novel connection between the biomolecule and cancer progression.
The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells
LabTalk Podcast - Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers
The Scientist Creative Services Team and 10x Genomics
The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells.
grey and purple cancer cells under a microscope
Cell Diversity Could Spell Trouble for Animal Models of Cancer
David Adam | Nov 19, 2021
Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.  
white mouse on wheel
Putative Exercise Hormone Irisin Boosts Mouse Brainpower
Sophie Fessl | Sep 10, 2021
Mice lacking irisin didn’t exhibit the cognition improvements that typically follow exercise, and in mouse models of Alzheimer’s disease, treatment with the hormone reduced cognitive decline.
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Heating Up CAR T Cells for Cancer Therapy
Roni Dengler, PhD
Heated gold nanoparticles unleash the therapeutic activity of engineered CAR T cells.
One hand holds a white envelope with a blue and red striped border, while a second hand places a clear sheet of plastic inside with small squares of paper on it
Freeze-Dried Mouse Sperm Sent by Postcard Produces Baby Mice
Amanda Heidt | Aug 5, 2021
Rather than relying on samples that need to be shipped in glass vials and on ice, researchers have developed a new method that allows mouse sperm to be sent easily at room temperature using standard mail delivery.
A black mouse runs on a yellow and green spinning wheel against a blue background
Exercising During Pregnancy Protects Mouse Offspring
Jack J. Lee | Aug 1, 2021
Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.
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Technique Talk: Redefining Mouse Transgenesis with CRISPR-Cas Technology
The Scientist Creative Services Team
Learn how CRISPR-Cas technology has revolutionized the creation of transgenic mouse models.
giraffe, genetics & genomics, CRISPR, gene editing, genome, physiology, hypertension, bone growth, techniques, mouse model
Genome Reveals Clues to Giraffes’ “Blatantly Strange” Body Shape
Amanda Heidt | Mar 19, 2021
The physiological demands of that long neck get support from a gene involved in strengthening bones and blood vessels, researchers find after inserting the sequence in mice.
Early Embryo Models Generated from Mouse Stem Cells
Abby Olena | Oct 17, 2019
Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.
Surveillance Gaps: How Cancer Arises
The Scientist Creative Services Team
Surveillance Gaps: How Cancer Arises
mouse in grass microbiome
New Mouse Model Predicts Two Clinical Trial Failures in Humans
Emma Yasinski | Aug 1, 2019
The lab animals had more natural microbiomes seeded by wild mice, unlike conventional models that are kept in sterile conditions.
AI mice in labs
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals
Thomas Hartung | May 1, 2019
Machine learning could be the key to reducing the use of animals in experiments.
The Scientist Speaks Podcast - Episode 10
The Scientist Creative Services Team
Cancer Immunotherapy: CRISPR Reveals Targets In Vivo
Image of the Day: Taken to Heart
Carolyn Wilke | Mar 14, 2019
By zooming in on a developing mouse heart, scientists are studying whether defects in vasculature contribute to a thin muscle wall.