Early Embryo Models Generated from Mouse Stem Cells
Early Embryo Models Generated from Mouse Stem Cells
Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.
Early Embryo Models Generated from Mouse Stem Cells
Early Embryo Models Generated from Mouse Stem Cells

Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.

Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.

mouse models
New Mouse Model Predicts Two Clinical Trial Failures in Humans
New Mouse Model Predicts Two Clinical Trial Failures in Humans
Emma Yasinski | Aug 1, 2019
The lab animals had more natural microbiomes seeded by wild mice, unlike conventional models that are kept in sterile conditions.
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals
Opinion: AI Beats Animal Testing at Finding Toxic Chemicals
Thomas Hartung | May 1, 2019
Machine learning could be the key to reducing the use of animals in experiments.
Image of the Day: Taken to Heart
Image of the Day: Taken to Heart
Carolyn Wilke | Mar 14, 2019
By zooming in on a developing mouse heart, scientists are studying whether defects in vasculature contribute to a thin muscle wall.
CAR T Cells Treat Lupus in Mice
CAR T Cells Treat Lupus in Mice
Abby Olena | Mar 6, 2019
T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.
Image of the Day: Mouse Tails
Image of the Day: Mouse Tails
Carolyn Wilke | Jan 24, 2019
Genetic mutations create lab mice with unusually long and short tails.
First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals
Abby Olena | Jan 23, 2019
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
Former Students Allege Mistreatment of Lab Animals at Calgary<strong>&nbsp;</strong>
Former Students Allege Mistreatment of Lab Animals at Calgary 
Catherine Offord | Aug 9, 2018
The university is carrying out a review of animal handling in the now-closed lab of neuropsychologist Vedran Lovic.
Ultrasound Fires Up the Auditory Cortex—Even Though Animals Can’t Hear It
Ultrasound Fires Up the Auditory Cortex—Even Though Animals Can’t Hear It
Abby Olena | May 24, 2018
Researchers have been using ultrasound to control brain activity, but studies in mice and guinea pigs show it also stimulates the auditory system, presenting a confounder for direct neural stimulation.
Reprogrammed Cells Treat Diabetes in Mice
Reprogrammed Cells Treat Diabetes in Mice
Abby Olena | May 2, 2018
Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.