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Analysis of Mouse Genes Reveals Novel Disease Models
Diana Kwon | Jun 26, 2017
The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes.
Study Bucks Belief that Oxidative Stress Is Bad for Pregnancy
Jef Akst | May 16, 2017
Mouse experiments indicate that, contrary to observations in pregnant women, reactive oxygen species contribute to normal placental development.
Immunological Differences Between Lab Mice and Wild Mice
Diana Kwon | May 5, 2017
Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.
Upgraded Photoswitch for Vision Repair
Jef Akst | Apr 13, 2017
Researchers improve on a technique to use a light-stimulated small molecule to confer longer-term photosensitivity to the retinal cells of blind mice.
CRISPR Corrects Duchenne-Causing Mutations
Anna Azvolinsky | Apr 12, 2017
Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.
Opinion: Canine Models for Alzheimer’s
Edward G. Barrett | Mar 1, 2017
For research on drugs to treat neurodegenerative diseases, dogs offer a better predictor of clinical outcomes.
Q&A: Zika Damages Mouse Testes, Reduces Fertility
Ben Andrew Henry | Oct 31, 2016
Michael Diamond of the Washington University School of Medicine in St. Louis and colleagues tracked the virus in the male mouse reproductive tract over several weeks.
Study: Enriched Housing Changes Murine T Cells
Jef Akst | Oct 3, 2016
Mice that live in a more-stimulating environment for two weeks appear to develop a more-inflammatory immune state that might help protect the animals against infection.
Stem Cells Drive Cancer Risk in Mice
Jef Akst | Aug 26, 2016
Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.
How Zika Infects Mother and Baby
Alison F. Takemura | Aug 25, 2016
The virus replicates in the vaginal tissue of pregnant mice and in the brains of their fetuses, researchers show.