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Driving Down Pests
Amy Lewis | Aug 28, 2017
A computer model estimates that gene-drive technology could wipe out populations of an invasive mammal on islands.
A Database of Genetic Differences Among Lab Mice
Ashley P. Taylor | Aug 7, 2017
Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.
Engineered Human Liver Tissue Grows in Mice
Anna Azvolinsky | Jul 19, 2017
Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.
Analysis of Mouse Genes Reveals Novel Disease Models
Diana Kwon | Jun 26, 2017
The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes.
Study Bucks Belief that Oxidative Stress Is Bad for Pregnancy
Jef Akst | May 16, 2017
Mouse experiments indicate that, contrary to observations in pregnant women, reactive oxygen species contribute to normal placental development.
Immunological Differences Between Lab Mice and Wild Mice
Diana Kwon | May 5, 2017
Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.
Upgraded Photoswitch for Vision Repair
Jef Akst | Apr 13, 2017
Researchers improve on a technique to use a light-stimulated small molecule to confer longer-term photosensitivity to the retinal cells of blind mice.
CRISPR Corrects Duchenne-Causing Mutations
Anna Azvolinsky | Apr 12, 2017
Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.
Opinion: Canine Models for Alzheimer’s
Edward G. Barrett | Mar 1, 2017
For research on drugs to treat neurodegenerative diseases, dogs offer a better predictor of clinical outcomes.
Q&A: Zika Damages Mouse Testes, Reduces Fertility
Ben Andrew Henry | Oct 31, 2016
Michael Diamond of the Washington University School of Medicine in St. Louis and colleagues tracked the virus in the male mouse reproductive tract over several weeks.