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The image shows different people exercising in a gym.
What Happens to Muscles During Exercise?
Exercise changes our muscles, but its molecular effects depend on the type of exercise. 
What Happens to Muscles During Exercise?
What Happens to Muscles During Exercise?

Exercise changes our muscles, but its molecular effects depend on the type of exercise. 

Exercise changes our muscles, but its molecular effects depend on the type of exercise. 

mTOR

Keeping Kidneys Healthy with a Hand from AI
Aparna Nathan, PhD | Dec 11, 2023 | 3 min read
Researchers found new mechanisms and drug targets for cystinosis.
Old brown dog with gray on its face and neck
Aging Dogs Provide Insights for Human Longevity
Hannah Thomasy, PhD, Drug Discovery News | Jul 19, 2023 | 6 min read
Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy, PhD | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
People holding signs
NYU Defends Against Backlash Over Potential Hire
Amanda Heidt | Apr 29, 2022 | 8 min read
Hundreds of the school’s faculty, students, and trainees are protesting its consideration of David Sabatini, who left his previous posts after alleged sexual misconduct.
David Sabatini seated, looking at camera
Cell Biologist David Sabatini Fired for Sexual Harassment
Shawna Williams | Aug 22, 2021 | 2 min read
The researcher, known for his work on the mTOR signaling pathway, is no longer with MIT’s Whitehead Institute or HHMI following an investigation into his conduct.
Two Experimental Drugs Reduce Infections in the Elderly
Sukanya Charuchandra | Jul 12, 2018 | 2 min read
Despite the treatment being given for only six weeks, the positive effects lasted for a year.
Compound Found in Red Wine Boosts Immune Cell Function
Catherine Offord | Oct 16, 2017 | 2 min read
At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 
Lasker Awards Go to a Cell Biologist and Cancer Vaccine Pioneers
Kerry Grens | Sep 6, 2017 | 2 min read
Douglas Lowy and John Schiller, whose work led to the HPV vaccine, and Michael Hall, who discovered the TOR pathway, win this year’s prizes.
Study: Eating Less Helps Worms Learn
Aggie Mika | Aug 2, 2017 | 2 min read
Food restriction decreases a metabolite that impedes associative learning in worms. 
Zika Virus Persists in the Nervous System and Elsewhere
Ruth Williams | Apr 27, 2017 | 3 min read
Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.
Mining the Outliers
Jef Akst | Apr 1, 2015 | 4 min read
Even when a clinical trial fails, some patients improve. What can researchers learn from these exceptional responders?
Mauro Costa-Mattioli: Memory’s Puppeteer
Kerry Grens | Feb 1, 2015 | 2 min read
Associate Professor, Department of Neuroscience, Baylor College of Medicine. Age: 39
Synaptic Pruning Improves Autism in Mice
Kerry Grens | Aug 25, 2014 | 2 min read
Fixing impaired pruning and autophagy signaling in neurons eases the symptoms of autism in a mouse model of the disorder.
Mutant Mice Live Longer
Kerry Grens | Aug 29, 2013 | 4 min read
Reducing the levels of mTOR in rodents extends their lifespan by about 20 percent, though not without consequences.
Blocking Memories to Treat Alcoholism
Bob Grant | Jun 25, 2013 | 2 min read
Targeting a molecular pathway involved with learning and memory helps rats with a taste for booze wean themselves off of the sauce.
David Sabatini: Demystifying mTOR
Cristina Luiggi | Mar 1, 2012 | 2 min read
Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44
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