A study explores how nuclear pore complexes are disrupted in Alzheimer’s disease.

The structure has a stress-resilient architecture reminiscent of suspension bridges.

Physical forces propagate from the outside of cells inward and vice versa.

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

See an animation that illustrates emerging insights into the inner ring structures of the nuclear pore complex.