Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.
Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Lipid Droplets Are Intracellular Bacteria-Fighting Machines

Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.

Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.

organelles
Infographic: Paraspeckle Form and Function
Infographic: Paraspeckle Form and Function
Archa Fox | Dec 1, 2019
What do scientists know about this membraneless nuclear body discovered less than two decades ago?
What Paraspeckles Can Teach Us About Basic Cell Biology
What Paraspeckles Can Teach Us About Basic Cell Biology
Archa Fox | Dec 1, 2019
Discovering a new type of subnuclear body taught me how pursuing the unexpected can lead to new insights—in this case, about long noncoding RNAs and liquid-liquid phase separation in cells.
Image of the Day: Liquid Compartments
Image of the Day: Liquid Compartments
Nicoletta Lanese | Aug 28, 2019
Membraneless organelles appear highly sensitive to ion concentrations in their environment.
Intracellular Magnetic Manipulations
Intracellular Magnetic Manipulations
Ruth Williams | Jun 1, 2019
Optimized tweezers enable precise 3-D manipulations of a cell’s organelles.
Bacteria Harbor Geometric “Organelles”
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
Infographic: Bacterial Microcompartments Basics
Infographic: Bacterial Microcompartments Basics
Amber Dance | Dec 1, 2018
These icosahedral structures are composed of proteins with unique geometric properties, which enable bacteria to employ them in a variety of situations.
Infographic: What Are Membraneless Organelles?
Infographic: What Are Membraneless Organelles?
Michael Crabtree, Tim Nott | Dec 1, 2018
The physical principles that dictate the formation of these subcellular compartments are simple, but they dictate the organelles’ complex functions.
These Organelles Have No Membranes
These Organelles Have No Membranes
Michael Crabtree, Tim Nott | Dec 1, 2018
From making ribosomes to protecting the integrity of the genome, these membraneless compartments play important roles in the cell. Their behavior is rooted in basic physics.
Nuclear Pores Come into Sharper Focus
Nuclear Pores Come into Sharper Focus
André Hoelz, Daniel H. Lin | Dec 1, 2016
Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.
Structural Details of Endoplasmic Reticulum Revealed
Structural Details of Endoplasmic Reticulum Revealed
Jef Akst | Oct 28, 2016
The ribosome-associated organelle consists of tightly packed tubes, not flat sheets as previously believed, according to new super-resolution microscopy images.
Mysterious Eukaryote Missing Mitochondria
Mysterious Eukaryote Missing Mitochondria
Anna Azvolinsky | May 12, 2016
Researchers uncover the first example of a eukaryotic organism that lacks the organelles.
Gia Voeltz: Cellular Cartographer
Gia Voeltz: Cellular Cartographer
Karen Zusi | Dec 1, 2015
Associate Professor, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder. Age: 43
A Vaulted Mystery
A Vaulted Mystery
Eufemia S. Putortì and Massimo P. Crippa | Aug 1, 2014
Nearly 30 years after the discovery of tiny barrel-shape structures called vaults, their natural functions remain elusive. Nevertheless, researchers are beginning to put these nanoparticles to work in biomedicine.
Contributors
Contributors
Abby Olena | Dec 1, 2013
Meet some of the people featured in the December 2013 issue of The Scientist.
Organelle Architecture
Organelle Architecture
Mary Beth Aberlin | Dec 1, 2013
There’s beauty in a cell’s marriage of structure and function.