Study Challenges CRISPR Method for Making Conditional Knockout Mice
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Researchers from 17 labs report low efficacy rates for the popular technique.
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Study Challenges CRISPR Method for Making Conditional Knockout Mice

Researchers from 17 labs report low efficacy rates for the popular technique.

Researchers from 17 labs report low efficacy rates for the popular technique.

replication
Latest Effort to Replicate Psych Studies Yields 62 Percent Success
Latest Effort to Replicate Psych Studies Yields 62 Percent Success
Kerry Grens | Aug 27, 2018
Among the experiments that came to the same result as the original, the effect size was smaller on average.
Replication Failures Highlight Biases in Ecology and Evolution Science
Replication Failures Highlight Biases in Ecology and Evolution Science
Yao-Hua Law | Aug 1, 2018
As robust efforts fail to reproduce findings of influential zebra finch studies from the 1980s, scientists discuss ways to reduce bias in such research.
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Abby Olena | Jul 12, 2018
A re-analysis of sequencing data from a 2016 study of these tiny metazoans reveals possible contamination, rather than an exchange of DNA among species.
Latest Reproducibility Project Study Fails to Replicate
Latest Reproducibility Project Study Fails to Replicate
Kerry Grens | Mar 13, 2018
Researchers did not observe the same link between a bacterium and human colon cancer that prior investigators had reported.
Pestilent Spread
Pestilent Spread
The Scientist Staff | Feb 28, 2018
See the University of Pennsylvania's David Roos explain the process of parasite replication.
One Way to Fix Reproducibility Problems: Train Scientists Better
One Way to Fix Reproducibility Problems: Train Scientists Better
Katarina Zimmer | Nov 28, 2017
Leonard Freedman, president of the Global Biological Standards Institute, discusses the causes of irreproducible science and his latest effort to spread best practices.
Final Nail Hammered into NgAgo Coffin
Final Nail Hammered into NgAgo Coffin
Kerry Grens | Aug 3, 2017
The paper describing the gene-editing method is retracted.
Preclinical Cancer Studies Not as Reproducible as Thought
Preclinical Cancer Studies Not as Reproducible as Thought
Jef Akst | Jun 30, 2017
Researchers overestimate the reliability of findings from animal studies that are part of the Reproducibility Project: Cancer Biology.
Cancer Studies Seem Replicable
Cancer Studies Seem Replicable
Kerry Grens | Jun 27, 2017
In the latest findings from the Reproducibility Project: Cancer Biology, independent researchers achieve results that mirror those of two earlier papers.