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“Xenobot” Living Robots Can Reproduce

Biological robots made from frog cells can replicate by smooshing loose cells into new robots—a reproduction method not seen in any other organism.

Written byChloe Tenn
Published Updated 3 min read
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Xenobots—living robots made from the stem cells of the African frog (Xenopus laevis)—had already impressed researchers by moving, healing themselves, and even spontaneously piling up debris that was strewn about. But when those small synthetic particles were replaced with loose frog cells, the little living bots did something remarkable: Xenobots “reproduced” by bringing those loose cells together, constructing new xenobots.1

“These are frog cells replicating in a way that is very different from how frogs do it. No animal or plant known to science replicates in this way,” Harvard University synthetic biologist and roboticist Sam Kriegman, co-lead author on the PNAS paper describing the discovery, said in a press release from Harvard University’s Wyss Institute.

Xenobots were first born when scientists extracted skin stem cells from frog embryos and cultured them in salt water. All on their own, the cells clumped together and cells on the outside of these clumps ...

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Meet the Author

  • young woman smiling

    Chloe Tenn is a graduate of North Carolina State University, where she studied neurobiology, English, and forensic science. Fascinated by the intersection of science and society, she has written for organizations such as NC Sea Grant and the Smithsonian. Chloe also works as a freelancer with AZoNetwork, where she ghostwrites content for biotechnology, pharmaceutical, food, energy, and environmental companies. She recently completed her MSc Science Communication from the University of Manchester, where she researched how online communication impacts disease stigma. You can check out more of her work here.

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