Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

stem cell
Spaceflight Alters Genes of Human Stem Cell–Derived Heart Cells
Spaceflight Alters Genes of Human Stem Cell–Derived Heart Cells
Emily Makowski | Nov 7, 2019
Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.
Neural Stem Cell Transplantation Crawls Toward the Clinic
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
Long-Lived Neural Stem Cells Identified in Living Mice
Long-Lived Neural Stem Cells Identified in Living Mice
Ashley Yeager | Oct 22, 2019
New, unpublished results show some of the cells produce new neurons for up to 90 days, much longer than a previously identified set of neural stem cells that only generate neurons for a month or two.
Early Embryo Models Generated from Mouse Stem Cells
Early Embryo Models Generated from Mouse Stem Cells
Abby Olena | Oct 17, 2019
Extended pluripotent stem cells from mice can self-organize to form blastocyst-like structures called blastoids that enable a closer look at early mammalian development.
Glowing Proteins Enable Stem Cell Stimulation for Stroke Recovery in Mice
Glowing Proteins Enable Stem Cell Stimulation for Stroke Recovery in Mice
Nicoletta Lanese | Oct 1, 2019
A new method helps neural stem cells form synaptic connections, thereby restoring lost brain function.
Google Bans Ads for Experimental Medical Treatments
Google Bans Ads for Experimental Medical Treatments
Ashley Yeager | Sep 9, 2019
The new policy will increase scrutiny and pressure on stem cell clinics, according to industry experts.
Northwestern University Stem Cell Therapy Clinic Closes Abruptly
Northwestern University Stem Cell Therapy Clinic Closes Abruptly
Katarina Zimmer | Sep 6, 2019
A Chicago-based center that has long operated a clinical trial program for stem cell therapies, has stopped recruiting further patients as its chief, Richard Burt, leaves for a research sabbatical.
First Human–Monkey Chimeras Developed in China
First Human–Monkey Chimeras Developed in China
Nicoletta Lanese | Aug 5, 2019
The researchers aim to grow transplantable human organs from primate embryos.
Experts Question Rationale for Stem Cell Trial for Autism
Experts Question Rationale for Stem Cell Trial for Autism
Hannah Furfaro | Aug 2, 2019
So far, the only evidence that treatments like this one work is anecdotal.