research reproducibility

Low participant numbers render the results of many studies based on brain scans unreliable, an analysis finds.

Malcolm Macleod, who helped develop these best practices, tells The Scientist how the new guidelines for manuscript publishing seek to support a push for transparent and thorough sharing of methods and data.

When 70 independent teams were tasked with analyzing identical brain images, no two teams chose the same approach and their conclusions were highly variable.

The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.

The Reproducibility Project: Cancer Biology initially aimed to replicate the results of 50 high-impact research articles.

The IoT can link up many facets of research—from laboratory equipment to ideas—but scientists must be ready for the questions its implementation could raise.

Including as few as two labs in a study improved the odds of getting the true effect size by as much as 23 percentage points, according to a replication model.

Researchers overestimate the reliability of findings from animal studies that are part of the Reproducibility Project: Cancer Biology.

A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

Companies make the antibodies, but it’s up to you to make sure they work in your experiments.