retina

A gene mutation causes porous gut and retinal barriers, allowing bacteria to travel from one to the other, triggering retinal degeneration in mice.

Mice have neurons that connect to both eyes but only propagate the signal from one or the other, simplifying the information sent to the cerebral cortex.

Spontaneous waves of nerve impulses flowing across the retina help mouse pups practice motion detection for when they eventually open their eyes.

A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.

While studying a degenerative eye disease, researchers find the first evidence that cells produce endogenous DNA in the cytoplasm. Drugs that block this activity are linked with reduced risk of atrophic age-related macular degeneration.

It’s not clear why the patients with Leber hereditary optic neuropathy, a mitochondrial disorder that causes blindness, also experienced the modest benefits in their untreated eye.

There are benefits of studying certain biological processes under microgravity, but whether those advantages outweigh the costs of getting experiments off Earth remains to be seen.

A trial is recruiting patients to test the gene-editing technology’s ability to treat an inherited form of blindness caused by a mutation in the CEP290 gene.

Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.

Researchers treat mice with retinitis pigmentosa using a gene therapy that reduces cone loss.

Researchers injected the retinas of mice with nanoparticles that bound to photoreceptors and converted near-infrared light to green light that the animals could see.

A missing microRNA leads to degenerating neurons and blindness in a fruit fly.

Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.

Blind rats are made to see after sheets of cells implanted into their eyes make themselves at home.

Ultraflexible mesh electrodes monitor the intact, functioning eyes of awake animals.

Selected Images of the Day from the-scientist.com

Human eye organoids could help scientists develop therapies for colorblindness.

A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.