Retinal Activity Prepares Blind Newborn Mice for Vision
Retinal Activity Prepares Blind Newborn Mice for Vision
Spontaneous waves of nerve impulses flowing across the retina help mouse pups practice motion detection for when they eventually open their eyes.
Retinal Activity Prepares Blind Newborn Mice for Vision
Retinal Activity Prepares Blind Newborn Mice for Vision

Spontaneous waves of nerve impulses flowing across the retina help mouse pups practice motion detection for when they eventually open their eyes.

Spontaneous waves of nerve impulses flowing across the retina help mouse pups practice motion detection for when they eventually open their eyes.

retina
How Early-Morning Light Exposure Makes Mice Less Depressed
How Early-Morning Light Exposure Makes Mice Less Depressed
Bianca Nogrady | Jul 22, 2021
A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.
Human Cells Can Synthesize DNA in Their Cytoplasm
Human Cells Can Synthesize DNA in Their Cytoplasm
Alejandra Manjarrez | Feb 8, 2021
While studying a degenerative eye disease, researchers find the first evidence that cells produce endogenous DNA in the cytoplasm. Drugs that block this activity are linked with reduced risk of atrophic age-related macular degeneration.
Gene Therapy in One Eye Improves Vision in Both Eyes
Gene Therapy in One Eye Improves Vision in Both Eyes
Abby Olena | Dec 11, 2020
It’s not clear why the patients with Leber hereditary optic neuropathy, a mitochondrial disorder that causes blindness, also experienced the modest benefits in their untreated eye.
Pharma Looks to Outer Space to Boost Drug R&D
Pharma Looks to Outer Space to Boost Drug R&D
Katarina Zimmer | Dec 1, 2020
There are benefits of studying certain biological processes under microgravity, but whether those advantages outweigh the costs of getting experiments off Earth remains to be seen.
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Catherine Offord | Jul 26, 2019
A trial is recruiting patients to test the gene-editing technology’s ability to treat an inherited form of blindness caused by a mutation in the CEP290 gene.
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Jef Akst | Apr 30, 2019
Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.
Image of the Day: Cone Preservation
Image of the Day: Cone Preservation
Chia-Yi Hou | Apr 30, 2019
Researchers treat mice with retinitis pigmentosa using a gene therapy that reduces cone loss.
Nanoparticles Let Mice See Near Infrared Light
Nanoparticles Let Mice See Near Infrared Light
Abby Olena | Feb 28, 2019
Researchers injected the retinas of mice with nanoparticles that bound to photoreceptors and converted near-infrared light to green light that the animals could see.
Image of the Day: In the Eye of a Fly
Image of the Day: In the Eye of a Fly
Carolyn Wilke | Feb 26, 2019
A missing microRNA leads to degenerating neurons and blindness in a fruit fly.
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Katarina Zimmer | Nov 28, 2018
Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.
Image of the Day: Retinal Transplant
Image of the Day: Retinal Transplant
Kerry Grens | Nov 7, 2018
Blind rats are made to see after sheets of cells implanted into their eyes make themselves at home.
Retina Recordings Reinvented
Retina Recordings Reinvented
Ruth Williams | Nov 1, 2018
Ultraflexible mesh electrodes monitor the intact, functioning eyes of awake animals.
Caught on Camera
Caught on Camera
The Scientist Staff | Nov 1, 2018
Selected Images of the Day from the-scientist.com
Image of Day: Retinas from Scratch
Image of Day: Retinas from Scratch
Ashley Yeager | Oct 12, 2018
Human eye organoids could help scientists develop therapies for colorblindness.
Reprogrammed Müller Glia Restore Vision in Mice
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
 Image of the Day: Throw the Switch
Image of the Day: Throw the Switch
Sukanya Charuchandra | Jun 27, 2018

A computer model of the eye can predict the consequences of altering the neural pathways of vision.

Image of the Day: An Eyeful
Image of the Day: An Eyeful
The Scientist Staff, The Scientist Staff | Apr 30, 2018
The physiological changes that can occur in the retinas of patients with cerebral malaria may provide a useful approach to diagnosis.
Prosthetic Retinas Help Blind Mice See
Prosthetic Retinas Help Blind Mice See
Ashley Yeager | Mar 6, 2018
Artificial photoreceptors made of nanowires help restore blind animals’ sensitivity to light.
Optogenetic Therapies Move Closer to Clinical Use
Optogenetic Therapies Move Closer to Clinical Use
Shawna Williams | Nov 16, 2017
With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.