A new study suggests that DNA synthesized in the cell cytoplasm drives retinal cell death in an advanced form of age-related macular degeneration, a leading cause of blindness.

While studying a degenerative eye disease, researchers find the first evidence that cells produce endogenous DNA in the cytoplasm. Drugs that block this activity are linked with reduced risk of atrophic age-related macular degeneration.

Mice who get less attention from their mothers have more copies of a common retrotransposon in the genomes of their hippocampal neurons.

No two neurons are alike. What does that mean for brain function?

Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.

Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.

Researchers examine the role of long interspersed element-1 retrotransposition in neuronal mosaicism.

From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome

Panoramix, a newly identified transcription repressor, takes the bounce out of jumping genes.

These mobile genetic elements can wreak havoc on the genome. Researchers are now trying to understand how such activity contributes to the aging process.

Researchers find evidence that transposable elements, also known as jumping genes, may contribute to the development of the psychiatric disorder.

Scientists show that horizontal transfer of a particular DNA sequence among a diverse range of vertebrates is more widespread than previously believed.

Retrotransposons contribute to genetic variability in human brain cells.

Genome sequence analysis confirms mobile genetic elements are a mutagenic mechanism in a variety of cancers.

Researchers show that retrotransposons can influence phenotypic variation by triggering early transcription termination.