RNA Interference Comes of Age
RNA Interference Comes of Age
The third FDA approval of an RNAi-based therapeutic marks the growing success of a technique that took two decades to get off the ground.
RNA Interference Comes of Age
RNA Interference Comes of Age

The third FDA approval of an RNAi-based therapeutic marks the growing success of a technique that took two decades to get off the ground.

The third FDA approval of an RNAi-based therapeutic marks the growing success of a technique that took two decades to get off the ground.

siRNA
Worm Parents Pass on Behaviors Epigenetically to Offspring
Worm Parents Pass on Behaviors Epigenetically to Offspring
Katarina Zimmer | Jun 7, 2019
Two research groups demonstrate that in Caenorhabditis elegans, behavioral traits can be passed down through the germline to future generations, even though they aren’t hard-wired.
Molecule Found in Huntington’s Patients Kills Cancer Cells
Molecule Found in Huntington’s Patients Kills Cancer Cells
Jim Daley | Feb 12, 2018
Researchers were able to slow tumor growth in a mouse model of human ovarian cancer. 
Mammalian Immunity: What’s RNAi Got to Do with It?
Mammalian Immunity: What’s RNAi Got to Do with It?
Shawna Williams | Jul 21, 2017
A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.
Making Micromotors Biocompatible
Making Micromotors Biocompatible
Jyoti Madhusoodanan | Jun 1, 2016
Researchers are developing potent ways to fuel and control the movement of micromotor devices.
RNA Ebola Drug Clears Animal Study
RNA Ebola Drug Clears Animal Study
Jef Akst | Apr 24, 2015
The short interfering RNA-based therapy TKM-Ebola protects monkeys from the viral strain still circulating in West Africa.
FDA OKs siRNA Ebola Drug
FDA OKs siRNA Ebola Drug
Kerry Grens | Sep 23, 2014
The US Food and Drug Administration gives the green light to deploy an experimental short interfering RNA treatment against Ebola.
Entry Requirements
Entry Requirements
Nicholette Zeliadt | Sep 1, 2014
Recent developments in cell transfection and molecular delivery technologies
Marburg Drug Shows Promise
Marburg Drug Shows Promise
Jyoti Madhusoodanan | Aug 21, 2014
Monkeys infected with lethal doses of Marburg virus were rescued by an experimental siRNA-based therapeutic, a study shows.
RNAi Remedy Lowers Cholesterol
RNAi Remedy Lowers Cholesterol
Abby Olena | Oct 3, 2013
A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.
Gene Silencing Is Golden
Gene Silencing Is Golden
Carina Storrs | Aug 1, 2013
A beginner’s how-to on RNAi screening in mammalian cells
Shushing RNA
Shushing RNA
Edyta Zielinska | Aug 1, 2013
The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.
(Re)Programming Director
Karen Hopkin | Oct 1, 2012
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
Dynamic Delivery
Ruth Williams | Jul 1, 2012
Microscopic sponges made entirely of RNA enable efficient gene silencing.
Seeds Inherit Memories of Enemies
Amy Coombs | May 31, 2012
Infested plants pass on a defense memory of pests and pathogens to help the next generation withstand invasions.
Color Explosion
Cristina Luiggi | Feb 3, 2012
A fluorescence microscopy image competition straddles the boundary of science and art.